Jobin Parker G, Stewart Connor, Vipani Aarshi, Perez-Alvarez Ingrid, Pepkowitz Samuel, Klapper Ellen, Berg Anders, Stillman Kaytlena, Torbati Sam, Kuo Alexander, Trivedi Hirsh, Yang Ju Dong, Steinberger Jonathan, Van Allan Richard J, Friedman Oren, Cardoza Kathryn, Ayoub Walid S
Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
Karsh Division Gastroenterology & Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA.
ACG Case Rep J. 2023 Dec 28;11(1):e01246. doi: 10.14309/crj.0000000000001246. eCollection 2024 Jan.
Mushroom (amatoxin) poisoning from ingestion is a rare but life-threatening medical emergency characterized by gastrointestinal symptoms before progression to multisystem organ failure in severe cases. Many therapies of amatoxin intoxication have been described, including supportive care, medical therapies, detoxification strategies, and liver transplant. The evidence supporting these therapies remains limited due to the rarity of amatoxin poisoning and challenge of a timely diagnosis. We report a case of amatoxin poisoning in Los Angeles causing severe liver injury without acute liver failure treated successfully using medical therapies, gallbladder drainage, and plasma exchange.
因误食蘑菇（鹅膏毒素）中毒是一种罕见但危及生命的医疗急症，其特征是在严重情况下，在发展为多系统器官衰竭之前会出现胃肠道症状。已经描述了许多治疗鹅膏毒素中毒的方法，包括支持治疗、药物治疗、解毒策略和肝移植。由于鹅膏毒素中毒罕见且及时诊断具有挑战性，支持这些治疗方法的证据仍然有限。我们报告了一例在洛杉矶发生的鹅膏毒素中毒病例，该病例导致严重肝损伤但无急性肝衰竭，通过药物治疗、胆囊引流和血浆置换成功治愈。
