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线粒体移植:向治疗应用和分子调控的进展

Mitochondrial transplantation: the advance to therapeutic application and molecular modulation.

作者信息

McCully James D, Del Nido Pedro J, Emani Sitaram M

机构信息

Department of Cardiac Surgery, Boston Children's Hospital, Boston, MA, United States.

Harvard Medical School, Boston, MA, United States.

出版信息

Front Cardiovasc Med. 2023 Dec 15;10:1268814. doi: 10.3389/fcvm.2023.1268814. eCollection 2023.

Abstract

Mitochondrial transplantation provides a novel methodology for rescue of cell viability and cell function following ischemia-reperfusion injury and applications for other pathologies are expanding. In this review we present our methods and acquired data and evidence accumulated to support the use of mitochondrial transplantation.

摘要

线粒体移植为缺血再灌注损伤后挽救细胞活力和细胞功能提供了一种新方法,并且其在其他病理状况中的应用正在不断扩展。在本综述中,我们展示了我们的方法以及为支持线粒体移植的应用而积累的已获得的数据和证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d9/10757322/65613e064650/fcvm-10-1268814-g001.jpg

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