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指甲化妆品中丙烯酸酯引起的接触性过敏:来自希腊的一项初步研究。

Contact allergy caused by acrylates in nail cosmetics: A pilot study from Greece.

作者信息

Gkousiaki Maria, Karalis Vangelis D, Kyritsi Aikaterini, Almpani Chara, Geronikolou Styliani, Stratigos Alexandros, Rallis Michail Christou, Tagka Anna

机构信息

Section of Pharmaceutical Technology, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.

Clinical Translational and Experimental Surgery Center, Biomedical Research Foundation of the Academy of Athens, Athens, Greece.

出版信息

Contact Dermatitis. 2024 Mar;90(3):273-279. doi: 10.1111/cod.14485. Epub 2024 Jan 2.

Abstract

BACKGROUND

The growing popularity of nail techniques based on acrylates has led to a higher frequency of sensitization in both nail technicians and users.

OBJECTIVES

The study aimed to assess cases of allergic contact dermatitis (ACD) caused by acrylates in individuals with occupational or non-occupational exposure to nail techniques.

METHODS

A preliminary study was conducted on 30 patients with ACD caused by acrylates in nail techniques, who were patch tested from September 2022 to March 2023 at the First Department of Dermatology and Venereology of Andreas Syggros Hospital, Athens, Greece.

RESULTS

Thirty female patients with ACD to acrylates were documented (15 users and 15 nail technicians and users). The most common allergens were: 2-hydroxyethyl methacrylate (HEMA), 2-hydroxypropyl methacrylate (HPMA) and ethyleneglycol dimethacrylate (EGDMA), which tested positive in all 30 patients (100.0%). Twenty patients (66.7%) had been exposed to dental procedures involving acrylates, before the onset of ACD. Nail technicians exhibited extensive skin lesions, 40.0% experienced ACD within the first year of work and 13.3% during their professional practice. Three of them (20.0%) had to discontinue their work.

CONCLUSION

Acrylates have been identified as potent allergens, necessitating the implementation of safety measures for the use of these chemicals in nail techniques.

摘要

背景

基于丙烯酸酯的美甲技术越来越受欢迎,这导致美甲师和使用者中过敏的频率更高。

目的

本研究旨在评估职业性或非职业性接触美甲技术的个体中由丙烯酸酯引起的过敏性接触性皮炎(ACD)病例。

方法

对30例因美甲技术中丙烯酸酯引起ACD的患者进行了初步研究,这些患者于2022年9月至2023年3月在希腊雅典安德烈亚斯·西格罗斯医院皮肤科和性病科一部接受了斑贴试验。

结果

记录了30例对丙烯酸酯过敏的女性患者(15名使用者和15名美甲师兼使用者)。最常见的过敏原是:甲基丙烯酸2-羟乙酯(HEMA)、甲基丙烯酸2-羟丙酯(HPMA)和乙二醇二甲基丙烯酸酯(EGDMA),这三种过敏原在所有30例患者中检测均呈阳性(100.0%)。20例患者(66.7%)在发生ACD之前曾接触过涉及丙烯酸酯的牙科手术。美甲师出现广泛的皮肤病变,40.0%在工作的第一年内出现ACD,13.3%在其职业实践期间出现。其中三人(20.0%)不得不停止工作。

结论

丙烯酸酯已被确定为强效过敏原,因此有必要在美甲技术中对这些化学品的使用实施安全措施。

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