Carlson J C, Perrin D G
J Reprod Fertil. 1979 May;56(1):175-80. doi: 10.1530/jrf.0.0560175.
Intracarotid infusion of LH-RH to female rabbits stimulated a significant increase in plasma LH concentration in the jugular vein. This response varied with the reproductive state of the animal, with a greater release occurring in oestrous (spontaneous or oestrogen-induced) and non-receptive does than in pseudopregnant or ovariectomized animals. If ovariectomized rabbits were pretreated with oestrogen, the pituitary response to LH-RH was restored. These findings suggest that there is little change in pituitary sensitivity to LH-RH infusion between oestrous and non-receptive rabbits, although pseudopregnancy (high physiological levels of progesterone) or ovariectomy inhibit its ability to respond to a releasing-hormone stimulus.
向雌性兔子颈内注入促黄体生成激素释放激素（LH-RH）可刺激颈静脉血浆中促黄体生成素（LH）浓度显著升高。这种反应随动物的生殖状态而变化，发情期（自然发情或雌激素诱导发情）和非接受期母兔比假孕或去卵巢动物释放的LH更多。如果对去卵巢兔子用雌激素进行预处理，垂体对LH-RH的反应会恢复。这些发现表明，发情期和非接受期兔子垂体对注入LH-RH的敏感性变化不大，尽管假孕（高生理水平的孕酮）或去卵巢会抑制其对释放激素刺激的反应能力。
