Liu Lu, Zhou Chenxia, Jiang Huimin, Wei Huimin, Zhou Yifan, Zhou Chen, Ji Xunming
Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100032, China.
Neurology and Intracranial Hypertension and Cerebral Venous Disease Center, National Health Commission of China, Xuanwu Hospital, Capital Medical University, Beijing, 100032, China.
Front Med. 2023 Dec;17(6):1047-1067. doi: 10.1007/s11684-023-1041-7. Epub 2024 Jan 2.
The Coronavirus disease 2019 (COVID-19) epidemic has triggered a huge impact on healthcare, socioeconomics, and other aspects of the world over the past three years. An increasing number of studies have identified a complex relationship between COVID-19 and stroke, although active measures are being implemented to prevent disease transmission. Severe COVID-19 may be associated with an increased risk of stroke and increase the rates of disability and mortality, posing a serious challenge to acute stroke diagnosis, treatment, and care. This review aims to provide an update on the influence of COVID-19 itself or vaccines on stroke, including arterial stroke (ischemic stroke and hemorrhagic stroke) and venous stroke (cerebral venous thrombosis). Additionally, the neurovascular mechanisms involved in SARS-CoV-2 infection and the clinical characteristics of stroke in the COVID-19 setting are presented. Evidence on vaccinations, potential therapeutic approaches, and effective strategies for stroke management has been highlighted.
在过去三年里，2019冠状病毒病（COVID-19）疫情对全球医疗保健、社会经济及其他方面都产生了巨大影响。尽管正在采取积极措施预防疾病传播，但越来越多的研究已经确定了COVID-19与中风之间存在复杂的关系。重症COVID-19可能与中风风险增加以及残疾率和死亡率上升有关，这对急性中风的诊断、治疗和护理构成了严峻挑战。本综述旨在提供关于COVID-19本身或疫苗对中风影响的最新信息，包括动脉性中风（缺血性中风和出血性中风）和静脉性中风（脑静脉血栓形成）。此外，还介绍了严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染所涉及的神经血管机制以及COVID-19背景下中风的临床特征。文中强调了疫苗接种、潜在治疗方法以及中风管理有效策略的相关证据。
