Department of Meridian & Acupoint, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
PLoS One. 2024 Jan 2;19(1):e0296326. doi: 10.1371/journal.pone.0296326. eCollection 2024.
As its prevalence increases and its association with cardiovascular disease and mortality is established, there is a need to improve prevention and management strategies for hypertension. Therefore, we aimed to compare differences in cardiovascular health status between men and women with hypertension defined by systolic blood pressure ≥140 mmHg and diastolic blood pressure ≥90 mmHg, and/or treatment with antihypertensive drugs. The association between cardiovascular health status and health-related quality of life was also evaluated. Additionally, a secondary analysis was performed on the cross-sectional data from 7306 adults with hypertension, ≥40 years of age between 2013 and 2018. Of this sample, 51.2% of patients were women from the Korean National Health and Nutrition Examination Survey. The seven Cardiovascular Health Metrics were used to quantify cardiovascular health status and the 5-dimensional European Quality of Life Questionnaire (EQ-5D) was used to evaluate health-related quality of life. A higher proportion of men than that of women was observed in the poor cardiovascular health score group [total score 0-7], with a higher proportion of women in the intermediate group [total score 8-10] and ideal group [total 11-14] (p<0.0001). The proportion of women in the EQ-5D index was higher than that of men in the poor and intermediate groups (p<0.0001), with no difference in the proportion of men and women in the ideal group (p = 0.1452). Furthermore, specific cardiovascular risk factors were different between men and women: women had lower physical activity level and higher prevalence of high cholesterol (≥200 mg/dl), and men had higher body mass indices and worse diet management. These findings indicate that prevention and management strategies for hypertension and cardiovascular health might need to differ for men and women to improve outcomes.
随着高血压患病率的增加及其与心血管疾病和死亡率的关联得到确立，需要改善高血压的预防和管理策略。因此，我们旨在比较收缩压≥140mmHg 和舒张压≥90mmHg 且/或接受降压药物治疗的男性和女性高血压患者之间心血管健康状况的差异。还评估了心血管健康状况与健康相关生活质量之间的关联。此外，还对 2013 年至 2018 年期间年龄≥40 岁的 7306 名高血压成年人的横断面数据进行了二次分析。在该样本中，51.2%的患者为来自韩国国家健康和营养检查调查的女性。使用七个心血管健康指标来量化心血管健康状况，使用 5 维欧洲生活质量问卷（EQ-5D）来评估健康相关生活质量。在心血管健康评分较差的患者中，男性的比例高于女性（总分 0-7），而在中等组[总分 8-10]和理想组[总分 11-14]中，女性的比例更高（p<0.0001）。女性在 EQ-5D 指数中的比例高于男性在较差和中等组中的比例（p<0.0001），而理想组中男女比例无差异（p=0.1452）。此外，男性和女性之间的特定心血管危险因素存在差异：女性体力活动水平较低，高胆固醇（≥200mg/dl）患病率较高，而男性体重指数较高，饮食管理较差。这些发现表明，为改善结局，高血压和心血管健康的预防和管理策略可能需要因性别而异。
