参与老年人衰老与认知健康评估研究的参与者的基线听力学特征描述。
Description of the Baseline Audiologic Characteristics of the Participants Enrolled in the Aging and Cognitive Health Evaluation in Elders Study.
作者信息
Sanchez Victoria A, Arnold Michelle L, Betz Joshua F, Reed Nicholas S, Faucette Sarah, Anderson Elizabeth, Burgard Sheila, Coresh Josef, Deal Jennifer A, Eddins Ann Clock, Goman Adele M, Glynn Nancy W, Gravens-Mueller Lisa, Hampton Jaime, Hayden Kathleen M, Huang Alison R, Liou Kaila, Mitchell Christine M, Mosley Thomas H, Neil Haley N, Pankow James S, Pike James R, Schrack Jennifer A, Sherry Laura, Teece Katherine H, Witherell Kerry, Lin Frank R, Chisolm Theresa H
机构信息
Department of Otolaryngology-Head and Neck Surgery, University of South Florida, Tampa.
Department of Communication Sciences and Disorders, University of South Florida, Tampa.
出版信息
Am J Audiol. 2024 Jan 2;33(1):1-17. doi: 10.1044/2023_AJA-23-00066.
PURPOSE
The Aging and Cognitive Health Evaluation in Elders (ACHIEVE) study is a randomized clinical trial designed to determine the effects of a best-practice hearing intervention versus a successful aging health education control intervention on cognitive decline among community-dwelling older adults with untreated mild-to-moderate hearing loss. We describe the baseline audiologic characteristics of the ACHIEVE participants.
METHOD
Participants aged 70-84 years ( = 977; = 76.8) were enrolled at four U.S. sites through two recruitment routes: (a) an ongoing longitudinal study and (b) de novo through the community. Participants underwent diagnostic evaluation including otoscopy, tympanometry, pure-tone and speech audiometry, speech-in-noise testing, and provided self-reported hearing abilities. Baseline characteristics are reported as frequencies (percentages) for categorical variables or medians (interquartiles, Q1-Q3) for continuous variables. Between-groups comparisons were conducted using chi-square tests for categorical variables or Kruskal-Wallis test for continuous variables. Spearman correlations assessed relationships between measured hearing function and self-reported hearing handicap.
RESULTS
The median four-frequency pure-tone average of the better ear was 39 dB HL, and the median speech-in-noise performance was a 6-dB SNR loss, indicating mild speech-in-noise difficulty. No clinically meaningful differences were found across sites. Significant differences in subjective measures were found for recruitment route. Expected correlations between hearing measurements and self-reported handicap were found.
CONCLUSIONS
The extensive baseline audiologic characteristics reported here will inform future analyses examining associations between hearing loss and cognitive decline. The final ACHIEVE data set will be publicly available for use among the scientific community.
SUPPLEMENTAL MATERIAL
目的
老年人衰老与认知健康评估（ACHIEVE）研究是一项随机临床试验，旨在确定最佳实践听力干预与成功老龄化健康教育对照干预对未治疗的轻度至中度听力损失的社区居住老年人认知衰退的影响。我们描述了ACHIEVE参与者的基线听力学特征。
方法
年龄在70 - 84岁（n = 977；平均年龄 = 76.8岁）的参与者通过两种招募途径在美国的四个地点入组：（a）一项正在进行的纵向研究，以及（b）通过社区全新招募。参与者接受了包括耳镜检查、鼓室图、纯音和言语测听、噪声中的言语测试在内的诊断评估，并提供了自我报告的听力能力。基线特征以分类变量的频率（百分比）或连续变量的中位数（四分位数间距，Q1 - Q3）报告。分类变量使用卡方检验，连续变量使用Kruskal - Wallis检验进行组间比较。Spearman相关性评估测量的听力功能与自我报告的听力障碍之间的关系。
结果
较好耳的四频率纯音平均中位数为39 dB HL，噪声中的言语表现中位数为6 dB SNR损失，表明在噪声中存在轻度言语困难。各地点之间未发现具有临床意义的差异。在招募途径方面发现了主观测量的显著差异。发现了听力测量与自我报告障碍之间的预期相关性。
结论
这里报告的广泛基线听力学特征将为未来检查听力损失与认知衰退之间关联的分析提供信息。最终的ACHIEVE数据集将公开提供给科学界使用。
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