Feder Katya Polena, Michaud David, McNamee James, Fitzpatrick Elizabeth, Ramage-Morin Pamela, Beauregard Yves
1Health Effects and Assessment Division, Health Canada, Ottawa, Ontario, Canada; 2Audiology & Speech-language Pathology Program, Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada; 3Health Analysis Division, Statistics Canada, Ottawa, Ontario, Canada; and 4Audiology Department, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Ear Hear. 2017 Jan/Feb;38(1):7-20. doi: 10.1097/AUD.0000000000000345.
There are no nationally representative hearing loss (HL) prevalence data available for Canadian youth using direct measurements. The present study objectives were to estimate national prevalence of HL using audiometric pure-tone thresholds (0.5 to 8 kHz) and or distortion product otoacoustic emissions (DPOAEs) for children and adolescents, aged 3 to 19 years.
This cross-sectional population-based study presents findings from the 2012/2013 Canadian Health Measures Survey, entailing an in-person household interview and hearing measurements conducted in a mobile examination clinic. The initial study sample included 2591 participants, aged 3 to 19 years, representing 6.5 million Canadians (3.3 million males). After exclusions, subsamples consisted of 2434 participants, aged 3 to 19 years and 1879 participants, aged 6 to 19 years, with valid audiometric results. Eligible participants underwent otoscopic examination, tympanometry, DPOAE, and audiometry. HL was defined as a pure-tone average >20 dB for 6- to 18-year olds and ≥26 dB for 19-year olds, for one or more of the following: four-frequency (0.5, 1, 2, and 4 kHz) pure-tone average, high-frequency (3, 4, 6, and 8 kHz) pure-tone average, and low-frequency (0.5, 1, and 2 kHz) pure-tone average. Mild HL was defined as >20 to 40 dB (6- to 18-year olds) and ≥26 to 40 dB (19-year olds). Moderate or worse HL was defined as >40 dB (6- to 19-year olds). HL in 3- to 5-year olds (n = 555) was defined as absent DPOAEs as audiometry was not conducted. Self-reported HL was evaluated using the Health Utilities Index Mark 3 hearing questions.
The primary study outcome indicates that 7.7% of Canadian youth, aged 6 to 19, had any HL, for one or more pure-tone average. Four-frequency pure-tone average and high-frequency pure-tone average HL prevalence was 4.7 and 6.0%, respectively, whereas 5.8% had a low-frequency pure-tone average HL. Significantly more children/adolescents had unilateral HL. Mild HL was significantly more common than moderate or worse HL for each pure-tone average. Among Canadians, aged 6 to 19, less than 2.2% had sensorineural HL. Among Canadians, aged 3 to 19, less than 3.5% had conductive HL. Absent DPOAEs were found in 7.1% of 3- to 5-year olds, and in 3.4% of 6- to 19-year olds. Among participants eligible for the hearing evaluation and excluding missing data cases (n = 2575), 17.0% had excessive or impacted pus/wax in one or both ears. Self-reported HL in Canadians, aged 6 to 19, was 0.6 E% and 65.3% (aged 3 to 19) reported never having had their hearing tested. E indicates that a high sampling variability is associated with the estimate (coefficient of variation between 16.6% and 33.3%) and should be interpreted with caution.
This study provides the first estimates of audiometrically measured HL prevalence among Canadian children and adolescents. A larger proportion of youth have measured HL than was previously reported using self-report surveys, indicating that screening using self-report or proxy may not be effective in identifying individuals with mild HL. Results may underestimate the true prevalence of HL due to the large number excluded and the presentation of impacted or excessive earwax or pus, precluding an accurate or complete hearing evaluation. The majority of 3- to 5-year olds with absent DPOAEs likely had conductive HL. Nonetheless, this type of HL which can be asymptomatic, may become permanent if left untreated. Future research will benefit from analyses, which includes the slight HL category, for which there is growing support, and from studies that identify factors contributing to HL in this population.
目前尚无加拿大青少年使用直接测量法得出的具有全国代表性的听力损失(HL)患病率数据。本研究的目的是使用听力计纯音阈值(0.5至8kHz)和/或畸变产物耳声发射(DPOAE)来估计3至19岁儿童和青少年的全国HL患病率。
这项基于人群的横断面研究展示了2012/2013年加拿大健康措施调查的结果,该调查包括一次上门入户访谈以及在移动检查诊所进行的听力测量。最初的研究样本包括2591名3至19岁的参与者,代表650万加拿大人(330万男性)。排除部分样本后,子样本包括2434名3至19岁的参与者和1879名6至19岁的参与者,他们均有有效的听力测量结果。符合条件的参与者接受了耳镜检查、鼓室图检查、DPOAE检查和听力测定。HL的定义为:对于6至18岁的儿童,一个或多个以下频率的纯音平均听阈>20dB,对于19岁的青少年,纯音平均听阈≥26dB:四频率(0.5、1、2和4kHz)纯音平均听阈、高频(3、4、6和8kHz)纯音平均听阈以及低频(0.5、1和2kHz)纯音平均听阈。轻度HL定义为>20至40dB(6至18岁)和≥26至40dB(19岁)。中度或更严重的HL定义为听阈>40dB(6至19岁)。3至5岁儿童(n = 555)的HL定义为未检测到DPOAE,因为未进行听力测定。使用健康效用指数Mark 3听力问题评估自我报告的HL。
主要研究结果表明,6至19岁的加拿大青少年中,7.7%的人存在任何一种纯音平均听阈的HL。四频率纯音平均听阈和高频纯音平均听阈的HL患病率分别为4.7%和6.0%,而低频纯音平均听阈HL的患病率为5.8%。明显更多的儿童/青少年患有单侧HL。对于每个纯音平均听阈,轻度HL比中度或更严重的HL更为常见。在6至19岁的加拿大人中,不到2.2%的人患有感音神经性HL。在3至19岁的加拿大人中,不到3.5%的人患有传导性HL。在3至5岁的儿童中,7.1%未检测到DPOAE,在6至19岁的儿童中,这一比例为3.4%。在符合听力评估条件且排除缺失数据的参与者中(n = 2575),17.0%的人一只或两只耳朵有过多或堵塞的脓液/耳垢。6至19岁的加拿大人自我报告的HL为0.6E%,65.3%(3至19岁)的人报告从未进行过听力测试。E表示该估计值具有较高的抽样变异性(变异系数在16.6%至33.3%之间),应谨慎解释。
本研究首次提供了加拿大儿童和青少年通过听力测量得出的HL患病率估计值。与之前使用自我报告调查得出的结果相比,有更多比例的青少年被测量出患有HL,这表明使用自我报告或代理报告进行筛查可能无法有效识别轻度HL患者。由于大量样本被排除,以及出现堵塞或过多的耳垢或脓液,妨碍了准确或完整的听力评估,结果可能低估了HL的真实患病率。大多数未检测到DPOAE的3至5岁儿童可能患有传导性HL。尽管如此,这种可能无症状的HL如果不治疗可能会变成永久性的。未来的研究将受益于包括轻度HL类别在内的分析,目前对该类别HL的支持越来越多,同时也将受益于识别该人群中导致HL的因素的研究。