Sánchez-Romero Luz M, Sagaceta-Mejía Janine, Mindell Jennifer S, Passi-Solar Álvaro, Bernabé-Ortiz Antonio, Tolentino-Mayo Lizbeth, Moody Alison, Scholes Shaun
Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC. USA.
Centro de Investigación en Nutrición y Salud, National Institute of Public Health, Mexico.
medRxiv. 2023 Dec 11:2023.12.10.23299756. doi: 10.1101/2023.12.10.23299756.
To quantify changes over time in waist circumference (WC) relative to body mass index (BMI) by sex in the Americas (U S, Mexico, Chile, Peru) and England.
Data from adults aged 25-64 years between 1997 and 2020 was analysed; US data was stratified by racial-ethnic groups. Sex-specific BMI and WC means, and obesity and abdominal obesity prevalence, were compared between the first and last surveys. Using data from all survey years, secular changes across the BMI and WC distributions were estimated applying quantile regression models. BMI was added as a predictor of WC to estimate secular changes in WC relative to BMI. Interaction terms were included in all models to evaluate differences by sex.
BMI and WC (except Peru) showed larger secular increases at the upper-tails of the distributions in both sexes. Increases at the 50 and 75 WC centiles relative to BMI were more pronounced in women than in men, with larger increases in US non-Hispanic whites and in England. In men, increases in WC independently of BMI were most evident in Mexico.
Disease risk associated with visceral fat, is potentially underestimated by national surveillance efforts that quantify changes only in BMI.
量化美洲（美国、墨西哥、智利、秘鲁）和英国按性别划分的腰围（WC）相对于体重指数（BMI）随时间的变化。
分析了1997年至2020年间25至64岁成年人的数据；美国数据按种族-族裔群体分层。比较了首次和末次调查之间按性别划分的BMI和WC均值，以及肥胖和腹型肥胖患病率。利用所有调查年份的数据，应用分位数回归模型估计BMI和WC分布的长期变化。将BMI作为WC的预测因子加入模型，以估计WC相对于BMI的长期变化。所有模型均纳入交互项以评估性别差异。
BMI和WC（秘鲁除外）在两性分布的上尾端均呈现出更大的长期增长。相对于BMI，女性在WC百分位数50和75处的增长比男性更明显，在美国非西班牙裔白人和英国增长幅度更大。在男性中，独立于BMI的WC增长在墨西哥最为明显。
仅量化BMI变化的国家监测工作可能会低估与内脏脂肪相关的疾病风险。
