脾切除术和半脾切除术对大鼠肺炎球菌感染及细菌清除的影响。
Effect of splenectomy and hemisplenectomy on pneumococcal infection and bacteria clearance in the rat.
作者信息
Pouchè A, Savoldi F, Colombi A, Tiberio G, Turano A
出版信息
Eur Surg Res. 1987;19(2):86-90. doi: 10.1159/000128685.
Median survival times 1 month after intraperitoneal inoculation of Streptococcus pneumoniae Felton UC 41 show that the difference between hemisplenectomized and control rats is not at all significant (chi 2 = 0.04). On the other hand, comparing splenectomized rats with hemisplenectomized and control rats taken together, there is a significant difference: 10% level (chi 2 = 2.84; 1 degree of freedom; p less than 0.10). The blood concentrations of pneumococci at different time intervals after inoculation do not differ between control and hemisplenectomized rats (F = 0.02; 1 and 135 degrees of freedom), but they differ very significantly when the splenectomized rats are compared with the hemisplenectomized rats and controls taken together (F = 10.00; 1 and 135 degrees of freedom; p less than 0.01).
腹腔接种肺炎链球菌费尔顿UC 41后1个月的中位生存时间表明，半脾切除大鼠与对照大鼠之间的差异完全不显著（卡方值=0.04）。另一方面，将脾切除大鼠与半脾切除大鼠及对照大鼠合并在一起进行比较时，存在显著差异：在10%水平（卡方值=2.84；自由度为1；p<0.10）。接种后不同时间间隔的肺炎球菌血浓度在对照大鼠和半脾切除大鼠之间没有差异（F=0.02；自由度为1和135），但当将脾切除大鼠与半脾切除大鼠及对照大鼠合并在一起进行比较时，差异非常显著（F=10.00；自由度为1和135；p<0.01）。
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