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亚美尼亚肺泡型棘球蚴病患者的低龄病例报告。

Young Age of Alveolar Echinococcosis Patient in Armenia: A Case Report.

作者信息

Manukyan Ani

机构信息

National Center for Disease Control and Prevention, Yerevan, Armenia.

出版信息

Iran J Parasitol. 2023 Oct-Dec;18(4):568-572. doi: 10.18502/ijpa.v18i4.14266.

Abstract

Human alveolar echinococcosis (AE) remains a serious public health concern in endemic areas and a challenge for clinicians. Here a confirmed case of human AE in a patient from Armenia who had not visited a known endemic area is reported. In October 2012, a 12-year-old girl from a little Armenian village, presented with paroxysmal pain in the right lumbar area to the children's medical center (MC). The girl mentioned having close contact with an animal, like a cat. She was admitted to the surgical department with a diagnosis of a malignant liver tumor in the right lobe. In November 2012, the patient underwent laparotomy, removal of the hepatic lesion and abdominal cavity drainage. The histopathological examination of the biopsy material confirmed the main diagnosis of liver AE with suppurative lesions. The patient was given albendazole (ABZ) following 20 days in the hospital, but she stopped receiving the preventive chemotherapy at home and even missed the dispensary visits. It later caused complications, and in July 2016, the child had once again surgery. In January 2017, the child was readmitted to the MC with no content from the external biliary drainage tube in the previous 6 hours. Bile flow improved after flushing the drainage with saline solution and suturing the enterostomy tube. In February 2017, the child visited MC for examination, and the drainage of the bile ducts was blocked, although she had neither discomfort nor jaundice. It was recommended to continue the patient's follow-up, to receive ABZ and to undergo a liver transplant surgery.

摘要

人体肺泡型棘球蚴病(AE)在流行地区仍然是一个严重的公共卫生问题,对临床医生来说也是一项挑战。本文报告了一例来自亚美尼亚的确诊人体AE病例,该患者未曾去过已知的流行地区。2012年10月,一名来自亚美尼亚一个小村庄的12岁女孩因右腰区阵发性疼痛前往儿童医疗中心(MC)就诊。女孩提到曾与一只类似猫的动物密切接触。她因右叶恶性肝肿瘤的诊断被收治入外科。2012年11月,患者接受了剖腹手术、肝病灶切除及腹腔引流。活检材料的组织病理学检查确诊为肝AE伴化脓性病变。患者在医院住院20天后接受了阿苯达唑(ABZ)治疗,但她在家中停止了预防性化疗,甚至错过了门诊随访。这后来引发了并发症,2016年7月,该患儿再次接受手术。2017年1月,该患儿因前6小时外部胆管引流管无引流物再次入住MC。用生理盐水冲洗引流管并缝合肠造口管后胆汁流量改善。2017年2月,该患儿前往MC检查,尽管她既无不适也无黄疸,但胆管引流受阻。建议继续对患者进行随访,接受ABZ治疗并接受肝移植手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9127/10758085/279c9b1a0b12/IJPA-18-568-g001.jpg

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