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Primary synovial sarcomas of the bone: clinical perspectives and correlation between the application of SS18-SSX and decalcification status.

作者信息

Ichikawa Jiro, Kawasaki Tomonori

机构信息

Department of Orthopaedic Surgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Chuo, Japan.

Department of Pathology, Saitama Medical University International Medical Center, Hidaka, Japan.

出版信息

Front Oncol. 2023 Dec 18;13:1265824. doi: 10.3389/fonc.2023.1265824. eCollection 2023.

DOI:10.3389/fonc.2023.1265824
PMID:38169964
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10759219/
Abstract
摘要

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Primary synovial sarcomas of the bone: clinical perspectives and correlation between the application of SS18-SSX and decalcification status.原发性骨滑膜肉瘤:临床观点及SS18-SSX应用与脱钙状态的相关性
Front Oncol. 2023 Dec 18;13:1265824. doi: 10.3389/fonc.2023.1265824. eCollection 2023.
2
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Correlating SS18-SSX immunohistochemistry (IHC) with SS18 fluorescent in situ hybridization (FISH) in synovial sarcomas: a study of 36 cases.滑膜肉瘤中 SS18-SSX 免疫组化(IHC)与 SS18 荧光原位杂交(FISH)的相关性:36 例研究。
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When used together SS18-SSX fusion-specific and SSX C-terminus immunohistochemistry are highly specific and sensitive for the diagnosis of synovial sarcoma and can replace FISH or molecular testing in most cases.当 SS18-SSX 融合特异性和 SSX C 端免疫组化联合使用时,对滑膜肉瘤的诊断具有高度特异性和敏感性,在大多数情况下可以替代 FISH 或分子检测。
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Frequent TRPS1 expression in synovial sarcoma is associated with SS18-SSX fusion oncoprotein activity.滑膜肉瘤中TRPS1的频繁表达与SS18-SSX融合癌蛋白活性相关。
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本文引用的文献

1
Primary synovial sarcoma of bone: a retrospective analysis of 25 patients.骨原发性滑膜肉瘤:25 例回顾性分析。
Histopathology. 2022 Mar;80(4):686-697. doi: 10.1111/his.14602. Epub 2022 Jan 18.
2
Clinical analysis of multimodal treatment for localized synovial sarcoma: A multicenter retrospective study.局限性滑膜肉瘤多模式治疗的临床分析:一项多中心回顾性研究
J Orthop Sci. 2023 Jan;28(1):261-266. doi: 10.1016/j.jos.2021.09.012. Epub 2021 Oct 27.
3
Bone sarcomas: ESMO-EURACAN-GENTURIS-ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up.骨肉瘤:ESMO-EURACAN-GENTURIS-ERN儿童癌症临床实践诊断、治疗及随访指南
Ann Oncol. 2021 Dec;32(12):1520-1536. doi: 10.1016/j.annonc.2021.08.1995. Epub 2021 Sep 6.
4
When used together SS18-SSX fusion-specific and SSX C-terminus immunohistochemistry are highly specific and sensitive for the diagnosis of synovial sarcoma and can replace FISH or molecular testing in most cases.当 SS18-SSX 融合特异性和 SSX C 端免疫组化联合使用时,对滑膜肉瘤的诊断具有高度特异性和敏感性,在大多数情况下可以替代 FISH 或分子检测。
Histopathology. 2020 Oct;77(4):588-600. doi: 10.1111/his.14190. Epub 2020 Sep 12.
5
Predictors and Survival of Patients with Osteosarcoma After Limb Salvage versus Amputation: A Population-Based Analysis with Propensity Score Matching.保肢与截肢治疗骨肉瘤患者的预后预测因素分析:基于倾向评分匹配的人群研究
World J Surg. 2020 Jul;44(7):2201-2210. doi: 10.1007/s00268-020-05471-9.
6
A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma.一种用于滑膜肉瘤诊断的新型 SS18-SSX 融合特异性抗体。
Am J Surg Pathol. 2020 Jul;44(7):922-933. doi: 10.1097/PAS.0000000000001447.
7
Decalcification of Breast Cancer Bone Metastases With EDTA Does Not Affect ER, PR, and HER2 Results.EDTA 脱钙处理乳腺癌骨转移不影响 ER、PR 和 HER2 检测结果。
Am J Surg Pathol. 2019 Oct;43(10):1355-1360. doi: 10.1097/PAS.0000000000001321.
8
p53 expression in normal paraffin-embedded tissue using different antibodies and antigen retrieval buffer systems.使用不同抗体和抗原修复缓冲液系统检测正常石蜡包埋组织中的p53表达。
Histopathology. 2003 Jan;42(1):83-7. doi: 10.1046/j.1365-2559.2003.01563.x.