Pollak P T, Vincken W, Munro I R, Cosio M G
Eur J Respir Dis. 1987 Feb;70(2):117-21.
A 42-year-old male hemophiliac with micrognathia caused by temperomandibular hemarthrosis was studied for obstructive sleep apnea and successfully treated without the use of a tracheostomy. Prevention of nocturnal hypoxemia by nasopharyngeal intubation was found to relieve daytime hypersomnolence while he was awaiting corrective jaw surgery. The association of obstructive sleep apnea with micrognathia secondary to hemophilia has not previously been reported to our knowledge.
一名42岁男性血友病患者，因颞下颌关节积血导致小颌畸形，针对其阻塞性睡眠呼吸暂停进行了研究，并在未行气管切开术的情况下成功治愈。在等待颌骨矫正手术期间，发现通过鼻咽插管预防夜间低氧血症可缓解日间嗜睡症状。据我们所知，此前尚未有阻塞性睡眠呼吸暂停与血友病继发小颌畸形相关联的报道。
