Khan M I
S Afr Med J. 1985 Jan 19;67(3):99-100.
A patient with congenital micrognathia, hypersomnia and severe pulmonary hypertension which resulted in sudden death during sleep is described. Hypersomnolence is a well-recognized manifestation of the pickwickian syndrome. A less recognized but similar disorder may affect patients with congenital or acquired micrognathia. The pathogenesis of this syndrome and obstructive sleep apnoea are reviewed. Tracheostomy timeously performed may be life-saving and the value of early resort to this apparently drastic procedure in a high-risk patient is emphasized.
本文描述了一名患有先天性小颌畸形、嗜睡症和严重肺动脉高压并在睡眠中突然死亡的患者。嗜睡是匹克威克综合征的一种公认表现。一种较少被认识但类似的病症可能会影响先天性或后天性小颌畸形患者。本文回顾了该综合征和阻塞性睡眠呼吸暂停的发病机制。及时进行气管造口术可能挽救生命，并强调了在高危患者中尽早采用这种看似激进的手术的价值。
