From the Departments of Radiology and Nuclear Medicine.
Pathology, Sultan Qaboos Comprehensive Cancer Care and Research Center (SQCCRC), Muscat, Oman.
Clin Nucl Med. 2024 Feb 1;49(2):e82-e84. doi: 10.1097/RLU.0000000000005029. Epub 2023 Dec 22.
Primary pulmonary paragangliomas are rare neuroendocrine tumors and are often discovered incidentally as nonfunctioning masses. We report a case of 58-year-old woman recently diagnosed with multifocal right breast cancer and suspicious right axillary lymph nodes. 18 F-FDG PET/CT showed a well-defined marginated lesion in the lower lobe of the right lung with intense FDG uptake. Findings were suspicious for pulmonary metastases. CT-guided biopsy results were consistent with a paraganglioma. Paragangliomas can mimic metastases, especially if they are large or have a high degree of FDG uptake, and careful evaluation of imaging features and clinical findings can help differentiate these entities. Most of the time biopsy is necessary to confirm the diagnosis.
原发性肺副神经节瘤是一种罕见的神经内分泌肿瘤，通常作为无功能肿块偶然发现。我们报告了一例 58 岁女性，最近诊断为多灶性右侧乳腺癌和可疑右侧腋窝淋巴结。18 F-FDG PET/CT 显示右肺下叶有一个边界清楚的局灶性病变，FDG 摄取强烈，提示肺部转移可能。CT 引导下活检结果符合副神经节瘤。副神经节瘤可能类似于转移瘤，尤其是当它们较大或 FDG 摄取程度较高时，仔细评估影像学特征和临床发现有助于区分这些实体。大多数情况下，需要进行活检以明确诊断。
