Ceska Gynekol. 2023;88(6):454-458. doi: 10.48095/cccg2023454.
: Objective: Endometriosis is a chronic disease with a relatively high prevalence in the female population. Both the disease itself and its surgical treatment can adversely affect the fertility of patients. For this reason, endometriosis is offered as a possible indication for fertility preservation by cryopreservation methods. The aim of this paper is to present the current knowledge on the options of fertility preservation in this subpopulation.
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Fertility preservation by cryopreservation methods has so far been used mainly in the care of women with cancer. With increasing experience, the effectiveness and availability of these methods have increased significantly and the indication spectrum has been extended to selected benign diseases such as endometriosis. Three techniques are currently established in practice: embryo cryopreservation, oocyte cryopreservation and ovarian tissue cryopreservation. Oocyte cryopreservation is the most commonly used technique, since it is the most advantageous for the patient and, according to the available data, is an effective way to increase the chances of future pregnancy for patients with endometriosis The purpose is to realize the protection of reproduction before the planned operation.
The diagnosis of endometriosis negatively affects the fertility of women. For some patients, the solution is fertility preservation by cryopreservation methods. Further clinical studies are needed to define exact, practically applicable indication criteria, potential risks of procedures and their benefits and cost-effectiveness.
目的：子宫内膜异位症是一种在女性人群中发病率相对较高的慢性疾病。该疾病本身及其手术治疗都可能对患者的生育能力产生不利影响。出于这个原因，子宫内膜异位症被提议通过冷冻保存方法作为一种可能的生育保存适应证。本文旨在介绍该亚人群生育保存的选择方案的现有知识。
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迄今为止，冷冻保存方法的生育保存主要用于癌症女性的护理。随着经验的增加，这些方法的有效性和可用性显著提高，适应证范围已扩展到子宫内膜异位症等选定的良性疾病。目前在实践中确立了三种技术：胚胎冷冻保存、卵母细胞冷冻保存和卵巢组织冷冻保存。卵母细胞冷冻保存是最常用的技术，因为它对患者最有利，并且根据现有数据，是增加子宫内膜异位症患者未来妊娠机会的有效方法。目的是在计划手术前实现对生殖的保护。
子宫内膜异位症的诊断会对女性的生育能力产生负面影响。对于一些患者来说，解决方法是通过冷冻保存方法进行生育保存。需要进一步的临床研究来定义确切的、实际可行的适应证标准、手术的潜在风险及其益处和成本效益。
