The Canadian Nosocomial Infection Surveillance Program: Keeping an eye on antimicrobial resistance in Canadian hospitals since 1995.

Surveillance is essential to inform evidence-based policy and control measures that combat antimicrobial resistance (AMR). The Canadian Nosocomial Infection Surveillance Program (CNISP) collaborates with 88 sentinel hospitals across Canada to conduct prospective surveillance of infections and antimicrobial resistant organisms important to hospital infection prevention and control. This article aims to increase awareness of CNISP hospital-based surveillance activities. Since its inception in 1995, the scope of CNISP has expanded to include community-associated infections, outpatient infections, viral respiratory infections such as coronavirus disease 2019, and emerging pathogens such as . This change in scope, along with expansion to include rural, northern and community hospitals, has improved the generalizability of CNISP surveillance data. To generate actionable surveillance data, CNISP integrates demographic and clinical data abstracted from patient charts with molecular and microbiological data abstracted from laboratory testing. These data serve as a benchmark for participating hospitals and stakeholders to assess the burden of AMR in hospital and intervene as needed. Further, CNISP surveillance data are now available on a public-facing data blog that provides interactive visualizations and data syntheses sooner than peer-reviewed publications. Future directions of CNISP include the Simplified Dataset, which will capture aggregate AMR data from hospitals outside of the CNISP network, surveillance in long-term care facilities and a fourth point prevalence survey. Given its strengths and future directions, CNISP is well positioned to serve as the reference point for hospital-based AMR data in Canada.