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一名21岁女性的胸骨孤立性朗格汉斯细胞组织细胞增多症。

Solitary Langerhans cell histiocytosis of the sternum in a 21-year-old woman.

作者信息

Soleimani Neda, Hosseinzadeh Massood, Amirian Armin, Hassani Masha, Mohammadzadeh Sahand

机构信息

Department of Pathology Shiraz University of Medical Sciences Shiraz Iran.

Thoracic and Vascular Surgery Research Center Shiraz University of Medical Science Shiraz Iran.

出版信息

Clin Case Rep. 2024 Jan 2;12(1):e8391. doi: 10.1002/ccr3.8391. eCollection 2024 Jan.

Abstract

Children are more likely to develop Langerhans cell histiocytosis (LCH), a rare disorder with an unknown cause. LCH often invades skeletal systems, while it has occasionally been seen in the sternum or ribs. The best course of treatment for single-site, skeletal LCH is yet unknown. We present an instance of sternal LCH with adult onset. By fusing and reconstructing chest computed tomography, it was possible to determine the extent of surrounding soft tissue invasion. Because LCH is so uncommon, it could be challenging to recall when we see a sternal lesion. Adult Patients who arrive with anterior chest discomfort and an osteolytic sternal lesion should include LCH on their differential diagnosis list.

摘要

儿童更容易患上朗格汉斯细胞组织细胞增多症(LCH),这是一种病因不明的罕见疾病。LCH常侵犯骨骼系统,偶尔也可见于胸骨或肋骨。单部位骨骼LCH的最佳治疗方案尚不清楚。我们报告一例成人发病的胸骨LCH病例。通过融合和重建胸部计算机断层扫描,可以确定周围软组织的侵犯范围。由于LCH非常罕见,当我们看到胸骨病变时,很难回忆起相关情况。出现前胸不适和溶骨性胸骨病变的成年患者,其鉴别诊断清单中应包括LCH。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c549/10761613/3f803591a4b1/CCR3-12-e8391-g004.jpg

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