Doctoral School, Medical Universty of Lublin, Lublin, Poland.
Department of Neurology, Medical University of Lublin, Lublin, Poland.
Neurol Neurochir Pol. 2024;58(1):66-74. doi: 10.5603/pjnns.96769. Epub 2024 Jan 4.
The aim of this study was to assess the validity and reliability of the Polish version of the Neuropathic Pain Questionnaire (NPQ-PL), and to compare it to other diagnostic tools.
Neuropathic pain is a burdensome condition, of which the exact prevalence is difficult to estimate. During initial screening, pain questionnaires are helpful in alerting clinicians about the need for further evaluation.
The NPQ-PL has been developed following the guidelines for translation and cultural adaptation. A total of 140 patients with chronic pain (ChP), 90 with neuropathic pain (NP), and 50 with nociceptive pain (NoP), were enrolled into this study.
The study group consisted of 60.71% women and 39.29% men; the mean age of patients (standard deviation, SD) was 53.22 years (15.81), and the average NPQ-PL score (SD) was 0.49 (1.27). Statistically significant relationships were found between higher age distribution and greater pain intensity in the NP group compared to the NoP group. There were also significant differences in pain levels between people of different ages, with the predominance in the elderly. Cronbach's alpha coefficient of the whole questionnaire was 0.85 and the intraclass correlation coefficient (ICC) for test-retest reliability was 0.635. Using receiver-operating characteristic (ROC) curve analysis, the area under the curve (AUC) was 0.97 and the best cut-off value was 0.002, which resulted in the highest sensitivity (93.3%) and specificity (96.0%).
The NPQ-PL is a valid tool for discriminating between neuropathic and nociceptive pain. It can be used by physicians of various disciplines when assessing patients with ChP of various origins.
本研究旨在评估波兰版神经性疼痛问卷(NPQ-PL)的有效性和可靠性,并将其与其他诊断工具进行比较。
神经性疼痛是一种负担沉重的疾病,其确切的患病率难以估计。在初步筛查中,疼痛问卷有助于提醒临床医生需要进一步评估。
NPQ-PL 是按照翻译和文化适应的指南开发的。共纳入 140 例慢性疼痛(ChP)患者、90 例神经性疼痛(NP)患者和 50 例伤害性疼痛(NoP)患者。
研究组女性占 60.71%,男性占 39.29%;患者的平均年龄(标准差)为 53.22 岁(15.81),NPQ-PL 评分(标准差)平均值为 0.49(1.27)。与 NoP 组相比,NP 组年龄分布较高和疼痛强度较大的患者存在统计学显著差异。不同年龄组的疼痛水平也存在显著差异,以老年人为主。整个问卷的克朗巴赫α系数为 0.85,测试-重测信度的组内相关系数(ICC)为 0.635。使用受试者工作特征(ROC)曲线分析,曲线下面积(AUC)为 0.97,最佳截断值为 0.002,这导致了最高的敏感性(93.3%)和特异性(96.0%)。
NPQ-PL 是区分神经性和伤害性疼痛的有效工具。它可以由各种学科的医生在评估各种来源的 ChP 患者时使用。