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评估复发性良性阵发性位置性眩晕患者的维生素 D 缺乏症:一项横断面研究。

Assessment of vitamin D deficiency in recurrent BPPV patients: A cross-sectional study.

机构信息

Department of Otorhinolaryngology-Head & Neck Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Department of Otorhinolaryngology-Head & Neck Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

出版信息

Am J Otolaryngol. 2024 May-Jun;45(3):104212. doi: 10.1016/j.amjoto.2023.104212. Epub 2024 Jan 2.

DOI:10.1016/j.amjoto.2023.104212
PMID:38176205
Abstract

PURPOSE

This study aimed to investigate the vitamin D deficiency of patients with BPPV recurrence and to evaluate the differences of 25-hydroxy vitamin D (25(OH)D) and serum calcium levels among gender and age categories.

METHODS

This cross-sectional study enrolled patients with BPPV. The diagnosis of BPPV was based on positional nystagmus and vertigo induced by certain head positions (The Dix-Hallpike maneuver and head roll tests). All patients' age, serum 25(OH)D, calcium measurements and recurrence data were collected and analyzed.

RESULTS

The median of 25(OH)D was 15.32 (IQR 10.61, 20.90) ng/ml. The recurrent group showed lower 25(OH)D levels than that of non-recurrent group [13.28 (IQR 9.47, 17.57) ng/ml vs 16.21 (IQR 11.49, 21.13) ng/ml]. There were significant differences of 25(OH)D levels among age categories. The proportion of vitamin D deficiency in patients ≥60 years old was lower than that in the other two groups.

CONCLUSION

Our study suggested that BPPV patients had a decreased 25(OH)D level and a high incidence of vitamin D deficiency. The 25(OH)D level of recurrent BPPV patients was lower than that in non-recurrent ones. Among them, the elderly group (≥60 years) took the preponderance, which had the lowest incidence of vitamin D deficiency and the highest incidence of vitamin D sufficiency.

摘要

目的

本研究旨在探讨复发性良性阵发性位置性眩晕(BPPV)患者的维生素 D 缺乏情况,并评估不同性别和年龄组患者的 25-羟维生素 D(25(OH)D)和血清钙水平的差异。

方法

本横断面研究纳入了 BPPV 患者。BPPV 的诊断依据是特定头位诱发的位置性眼球震颤和眩晕(Dix-Hallpike 试验和头脉冲试验)。收集并分析所有患者的年龄、血清 25(OH)D、钙测量值和复发数据。

结果

25(OH)D 的中位数为 15.32(IQR 10.61,20.90)ng/ml。复发组的 25(OH)D 水平低于非复发组[13.28(IQR 9.47,17.57)ng/ml vs 16.21(IQR 11.49,21.13)ng/ml]。25(OH)D 水平在不同年龄组之间存在显著差异。60 岁以上患者维生素 D 缺乏的比例低于其他两组。

结论

本研究表明,BPPV 患者 25(OH)D 水平降低,维生素 D 缺乏发生率较高。复发性 BPPV 患者的 25(OH)D 水平低于非复发性患者。其中,老年组(≥60 岁)占优势,维生素 D 缺乏发生率最低,维生素 D 充足发生率最高。

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