Department of Otorhinolaryngology-Head & Neck Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Department of Otorhinolaryngology-Head & Neck Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Am J Otolaryngol. 2024 May-Jun;45(3):104212. doi: 10.1016/j.amjoto.2023.104212. Epub 2024 Jan 2.
This study aimed to investigate the vitamin D deficiency of patients with BPPV recurrence and to evaluate the differences of 25-hydroxy vitamin D (25(OH)D) and serum calcium levels among gender and age categories.
This cross-sectional study enrolled patients with BPPV. The diagnosis of BPPV was based on positional nystagmus and vertigo induced by certain head positions (The Dix-Hallpike maneuver and head roll tests). All patients' age, serum 25(OH)D, calcium measurements and recurrence data were collected and analyzed.
The median of 25(OH)D was 15.32 (IQR 10.61, 20.90) ng/ml. The recurrent group showed lower 25(OH)D levels than that of non-recurrent group [13.28 (IQR 9.47, 17.57) ng/ml vs 16.21 (IQR 11.49, 21.13) ng/ml]. There were significant differences of 25(OH)D levels among age categories. The proportion of vitamin D deficiency in patients ≥60 years old was lower than that in the other two groups.
Our study suggested that BPPV patients had a decreased 25(OH)D level and a high incidence of vitamin D deficiency. The 25(OH)D level of recurrent BPPV patients was lower than that in non-recurrent ones. Among them, the elderly group (≥60 years) took the preponderance, which had the lowest incidence of vitamin D deficiency and the highest incidence of vitamin D sufficiency.
本研究旨在探讨复发性良性阵发性位置性眩晕(BPPV)患者的维生素 D 缺乏情况,并评估不同性别和年龄组患者的 25-羟维生素 D(25(OH)D)和血清钙水平的差异。
本横断面研究纳入了 BPPV 患者。BPPV 的诊断依据是特定头位诱发的位置性眼球震颤和眩晕(Dix-Hallpike 试验和头脉冲试验)。收集并分析所有患者的年龄、血清 25(OH)D、钙测量值和复发数据。
25(OH)D 的中位数为 15.32(IQR 10.61,20.90)ng/ml。复发组的 25(OH)D 水平低于非复发组[13.28(IQR 9.47,17.57)ng/ml vs 16.21(IQR 11.49,21.13)ng/ml]。25(OH)D 水平在不同年龄组之间存在显著差异。60 岁以上患者维生素 D 缺乏的比例低于其他两组。
本研究表明,BPPV 患者 25(OH)D 水平降低,维生素 D 缺乏发生率较高。复发性 BPPV 患者的 25(OH)D 水平低于非复发性患者。其中,老年组(≥60 岁)占优势,维生素 D 缺乏发生率最低,维生素 D 充足发生率最高。