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病程较长的尖锐湿疣患者细胞介导免疫功能降低。

Reduction of cell mediated immunity in patients with genital warts of long duration.

作者信息

Avgerinou G, Georgala S, Theodoridis A, Vareltzdis A, Stratigos J

出版信息

Genitourin Med. 1986 Dec;62(6):396-8. doi: 10.1136/sti.62.6.396.

DOI:10.1136/sti.62.6.396
PMID:3817815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1012007/
Abstract

Cell mediated immunity was studied by a leucocyte migration inhibition assay and by tuberculin and dinitrochlorobenzene skin tests in 30 patients with recurrent genital warts and in 34 healthy people (with no history of genital warts) who served as controls. Migration inhibition was significantly less in patients suffering from recurrences for more than one year than in controls (p less than 0.001). Dinitrochlorobenzene and tuberculin sensitivity were also found to be impaired in those with infection of long duration (p less than 0.001).

摘要

采用白细胞游走抑制试验、结核菌素试验和二硝基氯苯皮肤试验,对30例复发性尖锐湿疣患者及34名无尖锐湿疣病史的健康对照者进行细胞介导免疫研究。复发超过一年的患者,其游走抑制程度显著低于对照组(p<0.001)。长期感染者的二硝基氯苯和结核菌素敏感性也受到损害(p<0.001)。

相似文献

1
Reduction of cell mediated immunity in patients with genital warts of long duration.病程较长的尖锐湿疣患者细胞介导免疫功能降低。
Genitourin Med. 1986 Dec;62(6):396-8. doi: 10.1136/sti.62.6.396.
2
Thymus derived lymphocytes (T cells) in patients with genital warts.尖锐湿疣患者的胸腺来源淋巴细胞(T细胞)
Br J Vener Dis. 1984 Jun;60(3):186-8. doi: 10.1136/sti.60.3.186.
3
Specific immunity to human papilloma virus (HPV) in patients with genital warts.
Br J Vener Dis. 1978 Jun;54(3):172-5. doi: 10.1136/sti.54.3.172.
4
Circulating B and T lymphocyte subpopulations in patients with genital warts.
Br J Clin Pract. 1987 Feb;41(2):601-3.
5
[Delayed immune reactivity in patients with genital warts].
Z Hautkr. 1985 Nov 15;60(22):1809.
6
Hunan wart-virus antibodies in patients with genital and skin warts.
Acta Derm Venereol. 1978;58(5):427-32.
7
A placebo controlled observer blind immunocytochemical and histologic study of epithelium adjacent to anogenital warts in patients treated with systemic interferon alpha in combination with cryotherapy or cryotherapy alone.一项安慰剂对照、观察者盲法的免疫细胞化学和组织学研究,对象为接受全身干扰素α联合冷冻疗法或仅接受冷冻疗法治疗的尖锐湿疣患者肛门生殖器疣附近的上皮组织。
Genitourin Med. 1992 Apr;68(2):100-5. doi: 10.1136/sti.68.2.100.
8
Immunological events in regressing genital warts.生殖器疣消退过程中的免疫事件。
Am J Clin Pathol. 1994 Dec;102(6):768-74. doi: 10.1093/ajcp/102.6.768.
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Cell-mediated immune responses in patients with warts.
Br J Dermatol. 1975 Nov;93(5):553-6. doi: 10.1111/j.1365-2133.1975.tb02248.x.
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Intralesional immunotherapy for genital warts.尖锐湿疣的皮损内免疫疗法。
Arch Dermatol. 2005 Dec;141(12):1606-7. doi: 10.1001/archderm.141.12.1606.

引用本文的文献

1
Recurrent genital tract infection: a result of induced immunosuppression?复发性生殖道感染:诱导性免疫抑制的结果?
Genitourin Med. 1989 Dec;65(6):372-5. doi: 10.1136/sti.65.6.372.

本文引用的文献

1
The effect of certain infectious diseases on tuberculin allergy.某些传染病对结核菌素过敏的影响。
Tubercle. 1953 Feb;34(2):34-41. doi: 10.1016/s0041-3879(53)80013-9.
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Condylomata acuminata.
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Inhibition of delayed hypersensitivity reaction in skin (DNCB test) by 8-methoxypsoralen photochemotherapy. Possible basis for pseudo-promoting action in skin carcinogenesis?
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Natural history of genital warts.尖锐湿疣的自然病史。
Br J Vener Dis. 1971 Feb;47(1):1-13. doi: 10.1136/sti.47.1.1.
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A method for dinitrochlorobenzene contact sensitization. A clinicopathological study.二硝基氯苯接触致敏的一种方法。一项临床病理研究。
N Engl J Med. 1972 Feb 24;286(8):399-402. doi: 10.1056/NEJM197202242860804.
6
A leucocyte migration technique for in vitro detection of cellular (delayed type) hypersensitivity in man.一种用于体外检测人体细胞(迟发型)超敏反应的白细胞迁移技术。
Dan Med Bull. 1969 Jan;16(1):1-6.
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In vitro assay of cell-mediated immunity to human wart antigen.
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8
Serological studies in a student population prone to infection with human papilloma virus.对易感染人乳头瘤病毒的学生群体进行的血清学研究。
J Hyg (Lond). 1972 Dec;70(4):677-90. doi: 10.1017/s0022172400022531.
9
Serological studies with human papova (wart) virus.人乳头多瘤空泡病毒(疣病毒)的血清学研究。
J Hyg (Lond). 1970 Sep;68(3):479-90. doi: 10.1017/s0022172400042388.
10
Clinically evident, non-terminal infections with herpesviruses and the wart virus in immunosuppressed renal allograft recipients.免疫抑制的肾移植受者中临床上明显的非终末期疱疹病毒和疣病毒感染
Br Med J. 1970 Aug 1;3(5717):251-4. doi: 10.1136/bmj.3.5717.251.