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肝移植术后危及生命的电风暴:病例报告。

Life-Threatening Electrical Storm Following Liver Transplantation: A Case Report.

机构信息

Intensive Care Unit, Hospital Adventista Silvestre (HAS), Rio de Janeiro, RJ, Brazil.

Department of Gastrointestinal and Liver Transplant Surgery, Hospital Adventista Silvestre (HAS), Rio de Janeiro, RJ, Brazil.

出版信息

Am J Case Rep. 2024 Jan 5;25:e941932. doi: 10.12659/AJCR.941932.

DOI:10.12659/AJCR.941932
PMID:38178564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10775133/
Abstract

BACKGROUND Electrical storm is a rare but potentially life-threatening syndrome characterized by recurrent ventricular arrhythmias. Liver transplant recipients are at increased risk of developing electrical storms due to conditions that prolong QT intervals, such as cirrhotic cardiomyopathy. However, limited information exists on electrical storms in this specific population. This case report presents a patient who experienced 13 cardiac arrests during ventricular fibrillation following liver transplantation. CASE REPORT A 61-year-old woman with a medical history of diabetes, obesity, and cirrhosis due to non-alcoholic fatty liver disease underwent liver transplantation using a deceased donor's liver. Following the procedure, she developed a deterioration in her respiratory function, necessitating orotracheal intubation. Approximately 21 hours post-surgery, she experienced cardiac arrest during ventricular fibrillation, which was rapidly reversed with electrical defibrillation. However, the patient entered a state of electrical storm. Management involved antiarrhythmic medications and temporary transvenous cardiac pacing. She remained stable for 40 hours, but a dislodgment of the device triggered another episode of ventricular fibrillation, leading to her death. CONCLUSIONS This case report highlights the clinical presentation and challenges in managing electrical storms in liver transplant recipients. We hypothesize that cirrhotic cardiomyopathy could be the cause of her recurrent ventricular arrhythmias. Further studies are needed to better understand the underlying mechanisms and risk factors of this life-threatening syndrome in this population, which may enhance risk stratification and enable earlier intervention.

摘要

背景

电风暴是一种罕见但可能危及生命的综合征,其特征是反复出现室性心律失常。由于延长 QT 间期的情况,如肝硬化性心肌病,肝移植受者发生电风暴的风险增加。然而,关于这一特定人群的电风暴的信息有限。本病例报告介绍了一位肝移植后发生心室颤动 13 次心脏骤停的患者。

病例报告

一位 61 岁女性,有糖尿病、肥胖和非酒精性脂肪性肝病引起的肝硬化病史,接受了已故供体的肝脏进行肝移植。手术后,她的呼吸功能恶化,需要进行经口气管插管。大约手术后 21 小时,她发生了心室颤动的心脏骤停,迅速通过电除颤逆转。然而,患者进入了电风暴状态。治疗包括抗心律失常药物和临时经静脉心脏起搏。她稳定了 40 小时,但设备的移位引发了另一次心室颤动,导致她死亡。

结论

本病例报告强调了肝移植受者电风暴的临床表现和管理挑战。我们假设肝硬化性心肌病可能是她反复出现室性心律失常的原因。需要进一步研究以更好地了解这一危及生命的综合征在这一人群中的潜在机制和危险因素,这可能有助于风险分层并实现更早的干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1305/10775133/74222efbb31f/amjcaserep-25-e941932-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1305/10775133/74222efbb31f/amjcaserep-25-e941932-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1305/10775133/74222efbb31f/amjcaserep-25-e941932-g001.jpg

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