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心律失常风暴的多学科重症监护管理:JACC 最新技术评价

Multidisciplinary Critical Care Management of Electrical Storm: JACC State-of-the-Art Review.

机构信息

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

J Am Coll Cardiol. 2023 Jun 6;81(22):2189-2206. doi: 10.1016/j.jacc.2023.03.424.

Abstract

Electrical storm (ES) reflects life-threatening cardiac electrical instability with 3 or more ventricular arrhythmia episodes within 24 hours. Identification of underlying arrhythmogenic cardiac substrate and reversible triggers is essential, as is interrogation and programming of an implantable cardioverter-defibrillator, if present. Medical management includes antiarrhythmic drugs, beta-adrenergic blockade, sedation, and hemodynamic support. The initial intensity of these interventions should be matched to the severity of ES using a stepped-care algorithm involving escalating treatments for higher-risk presentations or recurrent ventricular arrhythmias. Many patients with ES are considered for catheter ablation, which may require the use of temporary mechanical circulatory support. Outcomes after ES are poor, including frequent ES recurrences and deaths caused by progressive heart failure and other cardiac causes. A multidisciplinary collaborative approach to the management of ES is crucial, and evaluation for heart transplantation or palliative care is often appropriate, even for patients who survive the initial episode.

摘要

电风暴(ES)反映了危及生命的心脏电不稳定性,即在 24 小时内出现 3 次或更多次室性心律失常发作。识别潜在的心律失常性心脏底物和可逆性触发因素至关重要,如果存在植入式心脏复律除颤器,则需要对其进行检测和编程。医疗管理包括抗心律失常药物、β-肾上腺素能阻滞剂、镇静和血液动力学支持。这些干预措施的初始强度应根据 ES 的严重程度使用阶梯式护理算法进行匹配,该算法涉及对高风险表现或复发性室性心律失常进行升级治疗。许多 ES 患者都被认为适合导管消融治疗,这可能需要使用临时机械循环支持。ES 后的结局较差,包括频繁的 ES 复发和因进行性心力衰竭和其他心脏原因导致的死亡。对 ES 的管理采用多学科协作方法至关重要,并且通常需要评估心脏移植或姑息治疗的可能性,即使对于最初发作后存活的患者也是如此。

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