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[针对下腰椎顶点的Lenke 5C型青少年特发性脊柱侧凸患者采用Cobb +1至Cobb融合策略的临床研究]

[Clinical study of the Cobb+1 to Cobb fusion strategy for Lenke 5C adolescent idiopathic scoliosis patients with the lower lumbar apex].

作者信息

Shu S B, Bao H D, Zhang X, Gu Q, Liu Z, Zhu Z Z, Qiu Y

机构信息

Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2024 Jan 2;104(1):10-15. doi: 10.3760/cma.j.cn112137-20230916-00476.

Abstract

To investigate the indications and surgical outcome of Cobb+1 to Cobb fusion strategy in Lenke 5C adolescent idiopathic scoliosis (AIS) patients with the lower lumbar apex. The clinical data of Lenke 5C AIS patients treated in Nanjing Drum Tower Hospital from August 2015 to December 2018 were retrospectively analyzed. The patients were followed-up for at least 2 years after surgery and treated with selective Cobb+1 to Cobb fusion strategy. The patients were divided into the normal lumbar apex group (apex location of the main curve was between T and L) and the lower lumbar apex group (apex location of the main curve was below the disc of L/L). The occurrence of proximal decompensation in the two groups was compared. In addition, according to whether the patients had proximal decompensation at the last follow-up, the patients in the lower lumbar apex group were further divided into proximal decompensation group and non-decompensation group. The radiographic parameters and Scoliosis Research Society-22 (SRS-22) scores of the two groups were compared. A total of 52 patients (19 cases in the normal lumbar apex group and 33 cases in the lower lumbar apex group), aged (15.3±1.6) years, were followed up for 2-5 (3.2±1.2) years. Six patients (6/19) in the normal lumbar apex group and 5 cases (15.2%) in the lower lumbar apex group showed proximal decompensation during follow-up, and the incidence was significantly higher in the normal lumbar apex group (=0.034). Within the lower lumbar apex group, the patients with proximal decompensation (=5) showed similar Risser grade, baseline thoracic Cobb angle, and main Cobb angle as those without proximal decompensation(=28), and the differences were all not statistically significant (all >0.05). However, the baseline thoracic/lumbar apical vertebra translation (AVT) ratio was significantly larger in patients with proximal decompensation (0.6±0.2 vs 0.4±0.2, =0.042), but the postoperative upper instrumented vertebra (UIV) tilt angle was similar (4.5°±2.3° vs 6.2°±3.4°, =0.312). Cobb+1 to Cobb fusion strategy, selecting UIV at 1 level above upper end vertebra (UEV), could be performed in Lenke 5C patients with the lower lumbar apex location. In addition, UIV could be selected at UEV+1 in patients with small baseline thoracic curve.

摘要

探讨Cobb +1至Cobb融合策略在腰椎顶椎位于下方的Lenke 5C型青少年特发性脊柱侧凸(AIS)患者中的适应证及手术疗效。回顾性分析2015年8月至2018年12月在南京鼓楼医院接受治疗的Lenke 5C型AIS患者的临床资料。患者术后至少随访2年,并采用选择性Cobb +1至Cobb融合策略进行治疗。将患者分为正常腰椎顶椎组(主弯顶椎位置在T10和L2之间)和低位腰椎顶椎组(主弯顶椎位置在L2/L3椎间盘以下)。比较两组近端失代偿的发生率。此外,根据末次随访时患者是否发生近端失代偿,将低位腰椎顶椎组患者进一步分为近端失代偿组和无失代偿组。比较两组的影像学参数和脊柱侧凸研究学会22项(SRS - 22)评分。共52例患者(正常腰椎顶椎组19例,低位腰椎顶椎组33例),年龄(15.3±1.6)岁,随访2 - 5(3.2±1.2)年。正常腰椎顶椎组6例(6/19)患者和低位腰椎顶椎组5例(15.2%)患者在随访期间出现近端失代偿,正常腰椎顶椎组的发生率显著更高(P = 0.034)。在低位腰椎顶椎组中,发生近端失代偿的患者(n = 5)与未发生近端失代偿的患者(n = 28)在Risser分级、基线胸弯Cobb角和主Cobb角方面相似,差异均无统计学意义(均P>0.05)。然而,发生近端失代偿的患者基线胸腰顶椎平移(AVT)比值显著更大(0.6±0.2比0.4±0.2,P = 0.042),但术后上固定椎(UIV)倾斜角相似(4.5°±2.3°比6.2°±3.4°,P = 0.312)。对于腰椎顶椎位于下方的Lenke 5C型患者,可采用Cobb +1至Cobb融合策略,在上端椎(UEV)上方1个节段选择UIV。此外,对于基线胸弯较小的患者,可在UEV +1选择UIV。

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