由地丝孢菌引起的暴发性真菌性角膜炎——一例报告。
Fulminant keratomycosis caused by Cylindrocarpon lichenicola- A case report.
机构信息
Cornea and Refractive Services, Aravind Eye Hospital and Post graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.
Paediatric and Strabismus Services, Aravind Eye Hospital and Post graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.
出版信息
Eur J Ophthalmol. 2024 May;34(3):NP8-NP12. doi: 10.1177/11206721231223542. Epub 2024 Jan 5.
PURPOSE
To report the clinical features, phylogenetic characteristics, microbiological characteristics, and the management of the rare emerging fungal species Cylindrocarpon lichenicola.
METHODS
A 55-year-old male farmer presented with a history of pain, redness, and defective vision. The corneal scrapings revealed septate hyphae macroconidia and multi-celled chlamydospores with lactophenol cotton blue mount. In addition, the culture revealed velvety to floccose, white growth with a pinkish-brown rim on the Sabouraud's dextrose agar. The growth was suggestive of the rare fungus Cylindrocarpon lichenicola.
RESULTS
The course of the infection was rapidly progressive, involving the entire cornea with descemetocele and impending perforation. Reinfection with the rapid spread of disease to the sclera was noted; finally, evisceration with scleral frill excision was done.
CONCLUSION
To our knowledge, this is the first case report of Fulminant Sclero Keratomycosis caused by Cylindrocarpon lichenicola.
目的
报告罕见真菌枝孢样枝孢菌的临床特征、系统发育特征、微生物学特征及处理方法。
方法
一名 55 岁男性农民出现疼痛、发红和视力受损。角膜刮片显示有分隔的菌丝、大分生孢子和乳酚棉蓝载片上的多细胞厚垣孢子。此外，培养显示出天鹅绒状至絮状、白色生长，萨布罗氏葡萄糖琼脂上有粉红色-棕色边缘。生长情况提示为罕见真菌枝孢样枝孢菌。
结果
感染过程迅速进展，累及整个角膜，伴有角膜后弹力层膨出和即将穿孔。注意到再次感染，疾病迅速蔓延至巩膜；最终，进行了眼球摘除术，并切除了巩膜边缘。
结论
据我们所知，这是首例由枝孢样枝孢菌引起的暴发性巩膜角膜炎病例报告。
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