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一项针对 40 岁及以上社区居住男性居民中膀胱过度活动症的 3 年纵向调查。

A 3-year longitudinal survey of overactive bladder in community-dwelling male residents aged 40 years and above.

机构信息

Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, Taiwan.

School of Medicine, Chung Shan Medical University, Taichung, Taiwan.

出版信息

Low Urin Tract Symptoms. 2021 Jul;13(3):356-360. doi: 10.1111/luts.12375. Epub 2021 Feb 17.

Abstract

OBJECTIVES

To evaluate the short-term evolution and risk factors of overactive bladder (OAB) in community-dwelling male residents aged 40 years and above in central Taiwan.

METHODS

This was a 3-year longitudinal cohort study. From January 2012 to December 2012, community residents aged 40 years and above, living in central Taiwan, were invited to participate in this study. A yearly Overactive Bladder Symptom Score (OABSS) questionnaire was used to assess the prevalence, incidence, remission, persistence, and relapse of OAB for three consecutive years. OAB was defined as total OABSS ≧4 and urgency score ≧2.

RESULTS

Nine hundred forty-one male residents aged ≧40 years were recruited. The prevalence of OAB was 15%. The male residents with OAB were older, had a history of urological surgery, were unemployed, had lower educational levels, and lower yearly incomes compared with male residents without OAB. The prevalence increased with age when stratified into different age cohorts (40-49, 7%; 50-59, 12.7%; 60-69, 18.2%; ≧70, 32%; P < .001). Age ≧60 (odds ratio [OR] 2.58; 95% CI, 1.62-4.11) and history of urological surgery (OR 2.85; 95% CI, 1.29-6.30) were the major risk factors after multivariable logistic regression analysis. Eight hundred participants completed all the 3 years' questionnaires. The second- and third-year incidence rates of OAB were 10% (69/691) and 6.2% (42/674), respectively. The remission rates were 47.7% (52/109) and 46% (58/126), respectively. The two-year OAB persistence rate was 30.3% (33/109).

CONCLUSIONS

The prevalence and yearly incidence of OAB are high in community-dwelling male residents aged ≧40 years in central Taiwan. Age is an important risk factor.

摘要

目的

评估台湾中部 40 岁及以上社区男性居民中膀胱过度活动症(OAB)的短期演变和危险因素。

方法

这是一项为期 3 年的纵向队列研究。2012 年 1 月至 12 月,邀请台湾中部 40 岁及以上的社区居民参加本研究。使用 3 年连续的膀胱过度活动症症状评分(OABSS)问卷评估 OAB 的患病率、发病率、缓解率、持续率和复发率。OAB 定义为总 OABSS≧4 且急迫评分≧2。

结果

共招募了 941 名 40 岁以上的男性居民。OAB 的患病率为 15%。与没有 OAB 的男性居民相比,患有 OAB 的男性居民年龄更大,有泌尿系统手术史,失业,教育程度较低,年收入较低。按不同年龄组分层,OAB 的患病率随年龄增加而增加(40-49 岁,7%;50-59 岁,12.7%;60-69 岁,18.2%;≧70 岁,32%;P<.001)。多变量逻辑回归分析后,年龄≧60 岁(比值比[OR] 2.58;95%可信区间[CI],1.62-4.11)和泌尿系统手术史(OR 2.85;95%CI,1.29-6.30)是主要危险因素。800 名参与者完成了所有 3 年的问卷。OAB 的第二年和第三年发病率分别为 10%(69/691)和 6.2%(42/674)。缓解率分别为 47.7%(52/109)和 46%(58/126)。两年的 OAB 持续率为 30.3%(33/109)。

结论

台湾中部 40 岁及以上社区男性居民中 OAB 的患病率和年发病率均较高。年龄是一个重要的危险因素。

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