Su Yuqin, Pan Xiaoli, Li Hansen, Zhang Guodong
Institute of Sport Science, College of Physical Education, Southwest University, Chongqing, China; College of Physical Education, Chongqing University of Posts and Telecommunications, Chongqing, China.
Institute of Sport Science, College of Physical Education, Southwest University, Chongqing, China.
Schizophr Res. 2024 Feb;264:236-247. doi: 10.1016/j.schres.2023.12.030. Epub 2024 Jan 6.
The objective of this meta-analysis is to evaluate and compare the effectiveness of different mind-body therapies in reducing the symptoms of schizophrenia.
A systematic search was performed using databases such as PubMed, Embase, Cochrane Library, Web of Science, and Scopus. Randomized controlled trials that assessed the effects of mind-body therapies on patients with schizophrenia were included. The search covered the period between the inception of each database and November 17th, 2022. The methodological quality of the trials was assessed using the Cochrane risk of bias tool. A network meta-analysis was conducted to compare the effects of various mind-body therapies, including Yoga, Mindfulness, Tai Chi, Baduanjin, and Yijinjing.
The analysis included 22 randomized controlled trials involving a total of 2064 subjects. The network meta-analysis revealed that Yoga and Mindfulness interventions were more effective than other mind-body therapies in reducing the symptoms of schizophrenia. Specifically, Yoga improved PANSS-positive symptom scores (SUCRA: 74.8 %) and PANSS-negative symptom scores (SUCRA: 80.4 %), whereas Mindfulness improved PANSS-positive symptom scores (SUCRA: 85.6 %).
The findings of this study indicate that Yoga may be a promising intervention for the treatment of schizophrenia. However, the small sample size and the low quality of the included studies have limited the generalizability of our findings Therefore, this study must be understood with caution, and further investigation is warranted when more relevant studies emerge.
本荟萃分析的目的是评估和比较不同身心疗法在减轻精神分裂症症状方面的有效性。
使用PubMed、Embase、Cochrane图书馆、科学网和Scopus等数据库进行系统检索。纳入评估身心疗法对精神分裂症患者影响的随机对照试验。检索涵盖每个数据库创建至2022年11月17日的时间段。使用Cochrane偏倚风险工具评估试验的方法学质量。进行网络荟萃分析以比较各种身心疗法的效果，包括瑜伽、正念、太极拳、八段锦和易筋经。
分析纳入了22项随机对照试验，共涉及2064名受试者。网络荟萃分析显示，瑜伽和正念干预在减轻精神分裂症症状方面比其他身心疗法更有效。具体而言，瑜伽改善了阳性和阴性症状量表（PANSS）的阳性症状评分（累积排序曲线下面积[SUCRA]：74.8%）和PANSS阴性症状评分（SUCRA：80.4%），而正念改善了PANSS阳性症状评分（SUCRA：85.6%）。
本研究结果表明，瑜伽可能是一种有前景的精神分裂症治疗干预措施。然而，纳入研究的样本量较小且质量较低，限制了我们研究结果的普遍性。因此，对本研究的解读必须谨慎，当有更多相关研究出现时，有必要进行进一步调查。
