Department of Pediatrics, Renaissance School of Medicine, SUNY Stony Brook, Stony Brook, New York, USA.
Mattel Children's Hospital, UCLA School of Medicine, Los Angeles, California, USA.
Clin Infect Dis. 2024 Jun 14;78(6):1629-1631. doi: 10.1093/cid/ciad778.
To breast feed or not has long been a difficult question for women with human immunodeficiency virus (HIV) in high-income countries, as undetectable HIV in maternal plasma does not translate to zero risk of transmission while breastfeeding, and clean water and formula are readily available. Recent, and more permissive, changes in US and other high-income-country guidelines regarding breastfeeding underscore this issue and acknowledge the information gaps that are essential for informed maternal choice and provider management. These include lack of guidance as to routine monitoring of mothers during lactation, type and length of prophylaxis for infants, and lack of data on factors associated with increased breast-milk viral load and risk of transmission. Ancillary to data are the education and staffing needs for providers participating in the management of breastfeeding individuals. Future studies of breast-milk transmission will need to evaluate these gaps so that we can move transmission to zero.
对于高收入国家的人免疫缺陷病毒 (HIV) 感染妇女来说,是否母乳喂养一直是一个难题,因为母体血浆中无法检测到 HIV 并不意味着母乳喂养时不存在传播风险,而且这些国家有清洁的水和配方奶粉供应。最近,美国和其他高收入国家的指南对母乳喂养的规定有所放宽,这突显了这一问题,并承认了在做出母婴知情选择和进行医护管理方面所必需的信息空白。这些空白包括在哺乳期对母亲进行常规监测、婴儿预防类型和时长方面缺乏指导,以及缺乏与增加母乳病毒载量和传播风险相关因素的数据。除此之外,还需要考虑参与母乳喂养管理的医护人员的教育和人员配备需求。未来对母乳传播的研究需要评估这些空白,以便我们能够将传播风险降到零。