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[棘球蚴病——诊断与流行病学的当前问题(作者译)]

[Echinococcosis.--Current problems of diagnosis and epidemiology (author's transl)].

作者信息

Disko R, Braveny I

出版信息

Med Klin. 1979 Aug 3;74(31):1159-63.

PMID:381883
Abstract

The indirect hemagglutination-test (IHA) and the indirect immunefluorescence-test are two modern methods for the serological diagnosis of an echinococcosis. If both tests are employed, the disease can be diagnosed with great reliability. A titer of 1 : 128 in the IHA makes the diagnosis of an echinococcosis very likely; a titer exceeding 1 : 1000 is significant. Serological tests of 36 patients with E. cysticus and E. alveolaris are evaluated; the interpretation of the results is discussed. In all patients the diagnosis was established between October 1977 and October 1978. In Germany the complement fixation test is commonly used to diagnose an echinococcosis. This test, however, is unreliable and fails in one third of all cases. It should be--as well as the Casoni skin-test--replaced by more sensitive and specific reactions. If the complement fixation test is positive, it might be used for postoperative controls. Compared to previous years the disease-rate among Germans is rising. The main reason seems to be the increasing tourism to foreign countries. Serological tests in small laboratories are unreliable and make an evaluation difficult. The diagnosis should be established in specialized centres.

摘要

间接血凝试验(IHA)和间接免疫荧光试验是棘球蚴病血清学诊断的两种现代方法。如果同时采用这两种试验,疾病诊断的可靠性会很高。IHA滴度为1:128时,棘球蚴病的诊断可能性很大;滴度超过1:1000则具有重要意义。对36例泡型棘球蚴病和囊型棘球蚴病患者的血清学检查结果进行了评估,并对结果的解读进行了讨论。所有患者的诊断均在1977年10月至1978年10月期间确定。在德国,补体结合试验常用于棘球蚴病的诊断。然而,该试验不可靠,在所有病例中有三分之一会出现误诊。它应该和卡索尼皮肤试验一样,被更敏感和特异的反应所取代。如果补体结合试验呈阳性,可用于术后复查。与前几年相比,德国人的发病率在上升。主要原因似乎是到国外旅游的人数增加。小型实验室的血清学检查不可靠,难以进行评估。诊断应在专业中心进行。

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