体外技术：它们能取代动物试验吗？
In-vitro techniques: can they replace animal testing?
作者信息
Pearson R M
出版信息
Hum Reprod. 1986 Dec;1(8):559-60. doi: 10.1093/oxfordjournals.humrep.a136473.
Abstract
In-vitro tests for the long-term safety evaluation of drugs offer certain advantages. Specific properties of drugs can be identified including mutagenic and carcinogenic effects. The mechanisms leading to toxicity can be assessed. Tissue from several species, including man, can be examined. These tests should reduce the number of animal tests required for screening new drugs.
摘要
药物长期安全性评估的体外试验具有一定优势。可以确定药物的特定性质，包括致突变和致癌作用。可以评估导致毒性的机制。可以检查包括人类在内的几种物种的组织。这些试验应能减少筛选新药所需的动物试验数量。
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