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接触力感应手动导管与远程磁导航消融治疗心房颤动的比较:单中心研究。

Contact force sensing manual catheter versus remote magnetic navigation ablation of atrial fibrillation: a single-center comparison.

机构信息

Department of Cardiology and Pneumology, Heart Center, University Medical Center, Robert-Koch-Str. 40, 37075, Göttingen, Germany.

DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, Göttingen, Germany.

出版信息

Heart Vessels. 2024 May;39(5):427-437. doi: 10.1007/s00380-023-02344-8. Epub 2024 Jan 8.

Abstract

BACKGROUND

Data comparing remote magnetic catheter navigation (RMN) with manual catheter navigation in combination with contact force sensing (MCN-CF) ablation of atrial fibrillation (AF) is lacking. The primary aim of the present retrospective comparative study was to compare the outcome of RMN versus (vs.) MCN-CF ablation of AF with regards to AF recurrence. Secondary aim was to analyze periprocedural risk, ablation characteristics and repeat procedures.

METHODS

We retrospectively analyzed 452 patients undergoing a total of 605 ablations of AF: 180 patients were ablated using RMN, 272 using MCN-CF.

RESULTS

Except body mass index there was no significant difference between groups at baseline. After a mean 1.6 ± 1.6 years of follow-up and 1.3 ± 0.4 procedures, 81% of the patients in the MCN-CF group remained free of AF recurrence compared to 53% in the RMN group (P < 0.001). After analysis of 153 repeat ablations (83 MCN-RF vs. 70 RMN; P = 0.18), there was a significantly higher reconnection rate of pulmonary veins after RMN ablation (P < 0.001). In multivariable Cox-regression analysis, RMN ablation (P < 0.001) and left atrial diameter (P = 0.013) was an independent risk factor for AF recurrence. Procedure time, radiofrequency application time and total fluoroscopy time and fluoroscopy dose were higher in the RMN group without difference in total number of ablation points. Complication rates did not differ significantly between groups (P = 0.722).

CONCLUSIONS

In our retrospective comparative study, the AF recurrence rate and pulmonary vein reconnection rate is significantly lower with more favorable procedural characteristics and similar complication rate utilizing MCN-CF compared to RMN.

摘要

背景

缺乏远程磁导管导航 (RMN) 与手动导管导航结合接触力感应 (MCN-CF) 消融治疗心房颤动 (AF) 的对比数据。本回顾性对照研究的主要目的是比较 RMN 与 MCN-CF 消融治疗 AF 的结果,重点关注 AF 复发。次要目的是分析围手术期风险、消融特征和重复手术。

方法

我们回顾性分析了 452 例共 605 例 AF 消融患者:180 例采用 RMN 消融,272 例采用 MCN-CF 消融。

结果

除体重指数外,两组基线时无显著差异。随访平均 1.6±1.6 年后和 1.3±0.4 次手术,MCN-CF 组 81%的患者无 AF 复发,而 RMN 组仅为 53%(P<0.001)。分析 153 例重复消融(83 例 MCN-RF 与 70 例 RMN;P=0.18)后,RMN 消融后肺静脉再连接率明显较高(P<0.001)。多变量 Cox 回归分析显示,RMN 消融(P<0.001)和左房直径(P=0.013)是 AF 复发的独立危险因素。RMN 组的手术时间、射频应用时间、总透视时间和透视剂量较高,但消融点数无差异。两组并发症发生率无显著差异(P=0.722)。

结论

在我们的回顾性对照研究中,与 RMN 相比,MCN-CF 具有较低的 AF 复发率和肺静脉再连接率,且具有更好的手术特征,且并发症发生率相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4680/11006819/e587c7302f45/380_2023_2344_Fig1_HTML.jpg

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