Department of Cardiology and Pneumology, Heart Center, University Medical Center, Göttingen, Germany.
DZHK (German Center for Cardiovascular Research), Göttingen, Germany.
Pacing Clin Electrophysiol. 2022 Jan;45(1):14-22. doi: 10.1111/pace.14392. Epub 2021 Oct 31.
Data comparing remote magnetic catheter navigation (RMN) with manual catheter navigation (MCN) ablation of atrial fibrillation (AF) is lacking. The aim of the present prospective observational study was to compare the outcome of RMN versus (vs.) MCN ablation of AF with regards to AF recurrence.
The study comprised 667 consecutive patients with a total of 939 procedures: 287 patients were ablated using RMN, 380 using MCN.
There was no significant difference between the groups at baseline. After 2.3 ± 2.3 years of follow-up, 23% of the patients in the MCN group remained free of AF recurrence compared to 13% in the RMN group (p < .001). After analysis of 299 repeat ablations (133 MCN, 166 RMN) there was a significantly higher reconnection rate of pulmonary veins after RMN ablation p < .001). In multivariable Cox-regression analysis, RMN ablation was an independent risk factor for AF recurrence besides age, persistent AF, number of isolated pulmonary veins, and left atrial diameter. Procedure time, radiofrequency application time and total number of ablation points were higher in the RMN group. Total fluoroscopy time and total fluoroscopy dose were significantly lower for RMN. Complication rates did not differ between groups (p = .842), although the incidence of significant pericardial effusion was higher in the MCN group (seven cases vs. three in RMN group).
In our study the AF recurrence rate and pulmonary vein reconnection rate is higher after RMN ablation with a similar complication rate but reduced probability of pericardial effusion when compared to MCN.
缺乏远程磁导管导航(RMN)与手动导管导航(MCN)消融心房颤动(AF)的比较数据。本前瞻性观察研究的目的是比较 RMN 与 MCN 消融 AF 在 AF 复发方面的结果。
该研究纳入了 667 例连续患者,共进行了 939 次手术:287 例患者接受 RMN 消融,380 例患者接受 MCN 消融。
两组患者在基线时无显著差异。在 2.3 ± 2.3 年的随访后,MCN 组中 23%的患者无 AF 复发,而 RMN 组中为 13%(p <.001)。对 299 例重复消融(133 例 MCN,166 例 RMN)进行分析后,RMN 消融后肺静脉再连接率明显较高(p <.001)。多变量 Cox 回归分析显示,除年龄、持续性 AF、孤立肺静脉数量和左心房直径外,RMN 消融也是 AF 复发的独立危险因素。RMN 组的手术时间、射频应用时间和消融点数总数均较高。RMN 组的总透视时间和总透视剂量明显较低。两组并发症发生率无差异(p =.842),但 MCN 组的大量心包积液发生率较高(7 例与 RMN 组的 3 例)。
与 MCN 相比,RMN 消融后的 AF 复发率和肺静脉再连接率较高,但心包积液的发生率较低。