Vos J H, van der Gaag I, van Dijk J E, Wouda W
J Comp Pathol. 1986 Nov;96(6):637-44. doi: 10.1016/0021-9975(86)90060-5.
Seven cases of cutaneous haemangiomas in young horses are described, characterized by scattered, well demarcated but unencapsulated lobules, consisting of capillary sized vascular structures, separated by strands of fibrous tissue. In one case, a more cellular variant was distinguished with minor vasoformative capacity. The morphological features of these haemangiomas are compatible with bovine cutaneous angiomatosis and human granuloma pyogenicum. The lesions are considered to be vascular tumours rather than hamartomas or granulation tissue and "lobular capillary haemangioma" is suggested to designate this type of haemangioma. In one tumour, cavernous vascular structures were also present in addition to the capillary structures and so this tumour is considered to be a combined capillary and cavernous haemangioma.
本文描述了7例幼马皮肤血管瘤病例,其特征为散在分布、边界清晰但无包膜的小叶,由毛细血管大小的血管结构组成,其间有纤维组织束分隔。在1例病例中,鉴别出一种细胞成分较多、血管形成能力较弱的变体。这些血管瘤的形态学特征与牛皮肤血管瘤病和人类化脓性肉芽肿相符。这些病变被认为是血管肿瘤而非错构瘤或肉芽组织,建议用“小叶状毛细血管瘤”来命名此类血管瘤。在1例肿瘤中,除毛细血管结构外还存在海绵状血管结构,因此该肿瘤被认为是毛细血管瘤和海绵状血管瘤的混合型。