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具有可互换收集器的经济实惠的实验室规模静电纺丝装置,用于定向纤维形成。

Affordable lab-scale electrospinning setup with interchangeable collectors for targeted fiber formation.

作者信息

Switz Alexi, Mishra Aditi, Jabech Katrina, Prasad Anamika

机构信息

Department of Biomedical Engineering, Florida International University, Miami, FL, United States.

Department of Mechanical and Materials Engineering, Florida International University, Miami, FL, United States.

出版信息

HardwareX. 2023 Dec 12;17:e00501. doi: 10.1016/j.ohx.2023.e00501. eCollection 2024 Mar.

DOI:10.1016/j.ohx.2023.e00501
PMID:38192608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10772283/
Abstract

The electrospinning method is increasingly in demand due to its capability to produce fibers in the nanometer to micrometer range, with applications in diverse fields including biomedical, filtration, energy storage, and sensing. Many of these applications demand control over fiber layout and diameter. However, a standard flat plate collector yields random fibers with limited control over diameter and density. Other viable solutions offering a higher level of control are either scarce or substantially expensive, impeding the accessibility of this vital technique. This study addresses the challenge by designing an affordable laboratory-scale electrospinning setup with interchangeable collectors, enabling the creation of targeted fibers from random, aligned, and coiled. The collectors include the standard flat plate and two additional designs, which are a rotating drum and a spinneret tip collector. The rotating drum collector has adjustable speed control to collect aligned fibers and exhibits stability even at high rotational speeds. The spinneret tip collector was designed to produce helically coiled fibers. The setup was validated by directed fiber formation using polycaprolactone (PCL), a biodegradable and FDA-approved polymer. Overall, the uniqueness of the design lies in its affordability, modifiability, and replicability using readily available materials, thus extending the reach of the electrospinning technique.

摘要

由于静电纺丝法能够生产纳米到微米范围内的纤维,并应用于生物医学、过滤、储能和传感等多个领域,因此其需求日益增加。这些应用中的许多都需要控制纤维的布局和直径。然而,标准的平板收集器会产生随机排列的纤维,对直径和密度的控制有限。其他能够提供更高控制水平的可行解决方案要么稀缺,要么成本高昂,这阻碍了这项重要技术的普及。本研究通过设计一种价格合理的实验室规模的静电纺丝装置来应对这一挑战,该装置配备了可互换的收集器,能够从随机、排列和卷曲的纤维中制造出目标纤维。收集器包括标准平板以及另外两种设计,即转鼓和喷丝头尖端收集器。转鼓收集器具有可调速度控制,可收集排列的纤维,即使在高转速下也能保持稳定。喷丝头尖端收集器旨在生产螺旋卷曲的纤维。该装置通过使用聚己内酯(PCL)进行定向纤维形成得到了验证,聚己内酯是一种可生物降解且经美国食品药品监督管理局批准的聚合物。总体而言,该设计的独特之处在于其价格合理、可修改且可使用现成材料进行复制,从而扩大了静电纺丝技术的应用范围。

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