Song Juhyun, Choi Seok-Yong
Department of Anatomy, Chonnam National University Medical School, Hwasun 58128, Korea.
Department of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Korea.
Exp Neurobiol. 2023 Dec 31;32(6):371-386. doi: 10.5607/en23040.
The hypothalamus is part of the diencephalon and has several nuclei, one of which is the arcuate nucleus. The arcuate nucleus of hypothalamus (ARH) consists of neuroendocrine neurons and centrally-projecting neurons. The ARH is the center where the homeostasis of nutrition/metabolism and reproduction are maintained. As such, dysfunction of the ARH can lead to disorders of nutrition/metabolism and reproduction. Here, we review various types of neurons in the ARH and several genetic disorders caused by mutations in the ARH.
下丘脑是间脑的一部分，有多个神经核，其中之一是弓状核。下丘脑弓状核（ARH）由神经内分泌神经元和向中枢投射的神经元组成。ARH是维持营养/代谢和生殖稳态的中心。因此，ARH功能障碍可导致营养/代谢和生殖紊乱。在此，我们综述ARH中的各种神经元类型以及由ARH突变引起的几种遗传性疾病。
