Hidayat Mariyah
Mariyah Hidayat University of Lahore, Lahore, Pakistan.
Pak J Med Sci. 2024 Jan-Feb;40(1Part-I):222-226. doi: 10.12669/pjms.40.1.8446.
Substantial change in climate over the years in South Asia is directly affecting the diet and health of the population. It is important to analyze the aftermath of this change and its impact on the thyroid status. In recent years, a complex interplay of the changing climate with the environmental, geographical and dietary factors has contributed to the continued prevalence of hypothyroidism in Pakistani women. To study the influence of various factors which might be aggravating hypothyroidism in the female population of Pakistan, a thorough search of literature was conducted of various databases including Google Scholar and PubMed. Google as a search engine was also explored. This included both interventional and observational studies, published in English, from the year 1950 onwards uptil June 2023. It also included WHO website and local news clips about the awareness campaigns on iodine deficiency over the past years. All studies conducted on females to diagnose hypothyroidism, with both positive and negative outcomes were included in this study. The factors contributing to hypothyroidism among the female population in Pakistan encompass the effects of climate change, both direct and indirect, topographical factor, indiscriminate use of hazardous pesticides, presence of chemical contaminants in food and water, and a lack of awareness among the public and healthcare professionals about the condition's symptoms and management.
多年来，南亚地区气候的巨大变化正在直接影响当地居民的饮食和健康。分析这种变化的后果及其对甲状腺状况的影响至关重要。近年来，气候变化与环境、地理和饮食因素之间复杂的相互作用导致巴基斯坦女性甲状腺功能减退症持续流行。为了研究可能加重巴基斯坦女性人群甲状腺功能减退症的各种因素的影响，我们对包括谷歌学术和PubMed在内的各种数据库进行了全面的文献检索。我们还探索了谷歌搜索引擎。这包括1950年至2023年6月期间以英文发表的干预性和观察性研究。它还包括世界卫生组织网站以及过去几年关于碘缺乏症宣传活动的当地新闻片段。所有针对女性诊断甲状腺功能减退症的研究，无论结果是阳性还是阴性，均纳入本研究。巴基斯坦女性人群中导致甲状腺功能减退症的因素包括气候变化的直接和间接影响、地形因素、滥用有害农药、食品和水中存在化学污染物，以及公众和医疗保健专业人员对该疾病症状和管理缺乏认识。
