Sayeed Saif, Mathur Manu Raj, Mishra Vijay Kumar, Nagrath Deepti, Watt Richard G
Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Centre for Dental Public Health and Primary Care, Institute of Dentistry, Queen Mary University of London, London, United Kingdom; Public Health Foundation of India, Gurugram, Haryana, India.
Indian J Dent Res. 2023 Jul-Sep;34(3):278-283. doi: 10.4103/ijdr.ijdr_104_23.
Analgesic use needs to be regulated due to its adverse effects. This study aimed to analyse the change in prescription rates and patterns of the analgesics prescribed for various oral conditions and to analyse their trends across different age groups and gender to promote rational prescription of drugs and eventually influence regulatory policies.
Secondary analysis was conducted on medical audit data collected from the private health sector in India. The prescription rate per 1000 persons per year was calculated from May 2013 to April 2016 using the mean projected population (PP) of India. Cross-tabulations were conducted to analyse the prescription rate and their changes across different age groups, gender and oral conditions.
The mean analgesic prescription rate was highest among the 20-40 age group, and the highest increase was noted in 'non-steroidal anti-inflammatory drug (NSAID) combinations' (3.56 per 1000 persons per year) from May 2013 to April 2016. The 'NSAID combinations' group was also the most prescribed medication across all the oral conditions, with 'diseases of hard tissues' having the highest prescription rate (41.4 and 45.6 per 1000 persons per year, respectively, for 2013-14 and 2015-16).
The results indicate an overall increase in the analgesic prescription rate, especially 'NSAID combinations' for each dental disease and age group, a finding that is hard to explain. Due to the lack of prescription guidelines in India, it is difficult to assess whether these analgesics were prescribed rationally or not.
由于镇痛药存在不良反应，其使用需要受到规范。本研究旨在分析针对各种口腔疾病所开具的镇痛药的处方率及模式变化，并分析其在不同年龄组和性别的趋势，以促进合理用药并最终影响监管政策。
对从印度私立医疗部门收集的医疗审计数据进行二次分析。使用印度的平均预测人口（PP）计算2013年5月至2016年4月期间每年每1000人的处方率。进行交叉列表分析，以分析不同年龄组、性别和口腔疾病的处方率及其变化。
20-40岁年龄组的平均镇痛药处方率最高，2013年5月至2016年4月期间“非甾体抗炎药组合”的增幅最大（每年每1000人3.56）。“非甾体抗炎药组合”组也是所有口腔疾病中处方最多的药物，“硬组织疾病”的处方率最高（2013-14年和2015-16年分别为每年每1000人41.4和45.6）。
结果表明镇痛药处方率总体上升，尤其是每种牙科疾病和年龄组的“非甾体抗炎药组合”，这一发现难以解释。由于印度缺乏处方指南，很难评估这些镇痛药的处方是否合理。
