Pandey Narayan Dutt, Bagul Sushilkumar Balasaheb, Talmohite Rajeev Ramesh, Choudhary Amit Kumar
Department of Oral and Maxillofacial Surgery, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
Department of Oral and Maxillofacial Surgery, S.M.B.T. Dental College and Hospital, Sangamner, Maharashtra, India.
Indian J Dent Res. 2023 Jul-Sep;34(3):332-334. doi: 10.4103/ijdr.ijdr_349_22.
Fibromyxoma is a locally aggressive rare benign tumor of mesenchymal origin with or without odontogenic epithelium. The etiology of this tumor remains unknown and it is responsible for approximately 3-8% of all cysts and tumors. Another locally destructive benign lesion is central giant cell granuloma (CGCG) which contains osteoclast-like multinucleated giant cells. CGCG accounts for about 7% of all benign jaw tumors, which usually affects younger females. A hybrid lesion with histologic features of both central fibromyxoma and CGCG has not been reported in the literature so far. In the present article, we report the first case of a hybrid tumor comprising odontogenic fibromyxoma with CGCG in a female along with a brief review of its clinical presentation, radiographic features, histological features, and management.
纤维黏液瘤是一种起源于间充质的局部侵袭性罕见良性肿瘤，可伴有或不伴有牙源性上皮。该肿瘤的病因尚不清楚，约占所有囊肿和肿瘤的3% - 8%。另一种具有局部破坏性的良性病变是中央巨细胞肉芽肿（CGCG），其含有破骨细胞样多核巨细胞。CGCG约占所有颌骨良性肿瘤的7%，通常影响年轻女性。迄今为止，文献中尚未报道过具有中央纤维黏液瘤和CGCG组织学特征的混合性病变。在本文中，我们报告了首例女性发生的包含牙源性纤维黏液瘤和CGCG的混合性肿瘤病例，并简要回顾了其临床表现、影像学特征、组织学特征及治疗方法。
