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感染期间的皮肤和鳃微生物群

Skin and Gill Microbiome during Infection.

作者信息

Godoy Marcos, Coca Yoandy, Suárez Rudy, Montes de Oca Marco, Bledsoe Jacob W, Burbulis Ian, Caro Diego, Pontigo Juan Pablo, Maracaja-Coutinho Vinicius, Arias-Carrasco Raúl, Rodríguez-Córdova Leonardo, Sáez-Navarrete César

机构信息

Centro de Investigaciones Biológicas Aplicadas (CIBA), Lago Panguipulli 1390, Puerto Montt 5480000, Región de Los Lagos, Chile.

Laboratorio de Biotecnología, Facultad de Ciencias de la Naturaleza, Escuela de Medicina Veterinaria, Universidad San Sebastián, Sede Patagonia, Lago Panguipulli 1390, Puerto Montt 5480000, Región de Los Lagos, Chile.

出版信息

Animals (Basel). 2023 Dec 27;14(1):97. doi: 10.3390/ani14010097.

Abstract

Maintaining the high overall health of farmed animals is a central tenant of their well-being and care. Intense animal crowding in aquaculture promotes animal morbidity especially in the absence of straightforward methods for monitoring their health. Here, we used bacterial 16S ribosomal RNA gene sequencing to measure bacterial population dynamics during infection. We observed a complex bacterial community consisting of a previously undescribed core pathobiome. Notably, we detected and on the skin ulcers of salmon infected with , while spp. were enriched on infected gills. The prevalence of these co-occurring networks indicated that coinfection with other pathogens may enhance pathogenicity.

摘要

维持养殖动物的高整体健康水平是其福祉和护理的核心原则。水产养殖中动物的高度密集会增加动物发病率,尤其是在缺乏直接监测其健康状况方法的情况下。在此,我们使用细菌16S核糖体RNA基因测序来测量感染期间的细菌种群动态。我们观察到一个复杂的细菌群落,其中包含一个先前未描述的核心病理生物群落。值得注意的是,我们在感染了[具体病原体名称]的鲑鱼的皮肤溃疡处检测到了[具体细菌名称1]和[具体细菌名称2],而[具体细菌名称3]属在感染的鳃中富集。这些共现网络的流行表明与其他病原体的共同感染可能会增强[具体病原体名称]的致病性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb20/10778177/2f7b4427d696/animals-14-00097-g0A1.jpg

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