Sales Sabrina, Lourenço Helena M, Bandarra Narcisa M, Afonso Cláudia, Matos Joana, Botelho Maria João, Pessoa Maria Fernanda, Félix Pedro M, Veronez Arthur, Cardoso Carlos
Division of Aquaculture and Upgrading (DivAV), Portuguese Institute for the Sea and Atmosphere (IPMA, IP), Rua Alfredo Magalhães Ramalho 6, 1495-006 Lisbon, Portugal.
Division of Oceanography and Marine Environment (DivOA), Portuguese Institute for the Sea and Atmosphere (IPMA, IP), 1495-165 Lisbon, Portugal.
Foods. 2023 Dec 21;13(1):35. doi: 10.3390/foods13010035.
Biological activity and bioactive compound content in sea cucumbers was assessed, considering , , , and as species and intestine, muscle band, respiratory tree, body wall, and gonads as tissues. had the lowest content in phenolic compounds and antioxidant activity in contrast to species. In the respiratory tree, the highest phenolic concentration was recorded in , 76.4 ± 1.2 mg GAE/100 g dw vs. 21.0-49.0 mg GAE/100 g dw in the other species. had the highest DPPH and FRAP results in the gonads, 13.6 ± 0.7 mg AAE/100 g dw vs. 2.6-3.5 mg AAE/100 g dw and 27.1 ± 0.3 μmol Fe/g dw vs. 8.0-15.9 μmol Fe/g dw, respectively. Overall, biomass presented the highest anti-inflammatory activity levels and the lowest anti-inflammatory levels. The respiratory tree was the most anti-inflammatory (measured by the inhibition of cyclooxygenase-2, COX-2) tissue in and (also the muscle band in this case), 76.3 ± 6.3% and 59.5 ± 3.6% COX-2 inhibition in 1 mg/mL aqueous extracts, respectively. The results demonstrated a variable bioactive potential and advantage in targeting antioxidant properties in the muscle band and anti-inflammatory activity in the respiratory tree, which may constitute a starting point for a biorefinery approach envisaging multiple applications.
评估了海参的生物活性和生物活性化合物含量，将[海参品种1]、[海参品种2]、[海参品种3]和[海参品种4]视为品种，将肠、肌带、呼吸树、体壁和性腺视为组织。与其他品种相比，[海参品种1]的酚类化合物含量和抗氧化活性最低。在呼吸树中，[海参品种2]的酚类浓度最高，为76.4±1.2毫克没食子酸当量/100克干重，而其他品种为21.0 - 49.0毫克没食子酸当量/100克干重。[海参品种3]在性腺中的DPPH和FRAP结果最高，分别为13.6±0.7毫克抗坏血酸当量/100克干重和27.1±0.3微摩尔铁/克干重，而其他品种分别为2.6 - 3.5毫克抗坏血酸当量/100克干重和8.0 - 15.9微摩尔铁/克干重。总体而言，[海参品种4]的生物量呈现出最高的抗炎活性水平，[海参品种1]的抗炎水平最低。呼吸树是[海参品种2]和[海参品种3]中抗炎性最强的组织（在这种情况下，肌带也是），在1毫克/毫升水提取物中，COX - 2抑制率分别为76.3±6.3%和59.5±3.6%。结果表明，在肌带中靶向抗氧化特性以及在呼吸树中靶向抗炎活性方面具有可变的生物活性潜力和优势，这可能构成设想多种应用的生物炼制方法的起点。
