Deaconu Silvia, Deaconu Alexandru, Marascu Gabriela, Stanculescu Mihaela Octavia, Cozma Dragoș, Cinteza Eliza, Vatasescu Radu
ARES Centers, 021967 Bucharest, Romania.
Cardiology Department, Clinic Emergency Hospital, 014461 Bucharest, Romania.
Diagnostics (Basel). 2023 Dec 23;14(1):33. doi: 10.3390/diagnostics14010033.
Atrial septal defect (ASD) represents the most common congenital heart defect identified in adulthood. Atrial and ventricular geometric remodeling due to intracardiac shunt increase the risk of arrhythmias, especially atrial fibrillation (AF). Clinical, echocardiography, electrocardiogram, and device-related predictors may be used to assess the risk of atrial arrhythmias after ASD closure. The underlying mechanisms in these patients are complex and at least in part independent of the structural remodeling secondary to hemodynamic overload. Device closure of the ASD itself and its timing impact future arrhythmia risk, as well as posing a challenge for when transseptal puncture is required. Sudden cardiac death (SCD) risk is higher than in the general population and an implantable cardioverter-defibrillator (ICD) may be indicated in selected cases.
房间隔缺损（ASD）是成年期最常见的先天性心脏病。心内分流导致的心房和心室几何重塑增加了心律失常的风险，尤其是心房颤动（AF）。临床、超声心动图、心电图和与器械相关的预测指标可用于评估ASD封堵术后房性心律失常的风险。这些患者的潜在机制很复杂，至少部分独立于血流动力学过载继发的结构重塑。ASD本身的器械封堵及其时机影响未来心律失常风险，同时也给何时需要经房间隔穿刺带来挑战。心脏性猝死（SCD）风险高于普通人群，在某些特定情况下可能需要植入式心律转复除颤器（ICD）。
