鼻窦恶性肿瘤治疗后监测计划的作用：417例患者分析
The role of a post therapeutic surveillance program for sinonasal malignancies: Analysis of 417 patients.
作者信息
Zocchi Jacopo, Pietrobon Giacomo, Campomagnani Isotta, Riggi Emilia, Veronesi Giovanni, Borchini Rossana, Pellini Raul, Volpi Luca, Bignami Maurizio, Castelnuovo Paolo
机构信息
Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences, University of Insubria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Research Center in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria.
出版信息
Head Neck. 2020 May;42(5):963-973. doi: 10.1002/hed.26069. Epub 2019 Dec 31.
BACKGROUND
Post therapeutic surveillance of head and neck neoplasms is a still debated issue in the current literature: although different works tried to establish frequency, modality, and efficacy of a routine follow-up, little evidence has been produced, in particular considering only sinonasal malignancies.
METHODS
A retrospective review of patients treated for sinonasal malignancies in a single tertiary center and followed through a regular program of follow-up was carried out. Rate of recurrence, location, timing, diagnosis, and salvage treatment were the main data analyzed.
RESULTS
Of note, 417 patients were included in the study and 117 experienced at least one relapse. Staging, histological type, and previous treatment represent the main clinical factors to be considered to stratify patient's risk of recurrence.
CONCLUSION
A regular post therapeutic surveillance can provide an early recurrence detection for patients treated for sinonasal malignancies, offering opportunity for salvage treatment in a high percentage of patients.
背景
头颈部肿瘤的治疗后监测在当前文献中仍是一个有争议的问题：尽管不同的研究试图确定常规随访的频率、方式和疗效，但几乎没有证据，特别是仅考虑鼻窦恶性肿瘤时。
方法
对在单个三级中心接受鼻窦恶性肿瘤治疗并通过常规随访计划进行随访的患者进行回顾性研究。复发率、位置、时间、诊断和挽救治疗是主要分析的数据。
结果
值得注意的是，417名患者纳入研究，117名经历了至少一次复发。分期、组织学类型和既往治疗是分层患者复发风险时需考虑的主要临床因素。
结论
定期的治疗后监测可为接受鼻窦恶性肿瘤治疗的患者提供早期复发检测，为高比例患者提供挽救治疗机会。
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