• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Cancer-Associated Fibroblasts: Major Co-Conspirators in Tumor Development.癌症相关成纤维细胞:肿瘤发展中的主要同谋者
Cancers (Basel). 2024 Jan 2;16(1):211. doi: 10.3390/cancers16010211.
2
The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities.肿瘤微环境作为乳腺癌干性和治疗抵抗的驱动因素:新的挑战和治疗机会。
Cell Oncol (Dordr). 2021 Dec;44(6):1209-1229. doi: 10.1007/s13402-021-00634-9. Epub 2021 Sep 16.
3
DT-13 inhibits breast cancer cell migration via non-muscle myosin II-A regulation in tumor microenvironment synchronized adaptations.DT-13 通过肿瘤微环境同步适应中的非肌肉肌球蛋白 II-A 调控抑制乳腺癌细胞迁移。
Clin Transl Oncol. 2020 Sep;22(9):1591-1602. doi: 10.1007/s12094-020-02303-z. Epub 2020 Feb 13.
4
Cancer-Associated Fibroblasts in Gastrointestinal Cancers: Unveiling Their Dynamic Roles in the Tumor Microenvironment.癌症相关成纤维细胞在胃肠道癌症中的作用:揭示其在肿瘤微环境中的动态作用。
Int J Mol Sci. 2023 Nov 19;24(22):16505. doi: 10.3390/ijms242216505.
5
Spatial transcriptomics atlas reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment components in colorectal cancer.空间转录组图谱揭示结直肠癌中肿瘤相关成纤维细胞与肿瘤微环境成分的相互作用。
J Transl Med. 2022 Jul 6;20(1):302. doi: 10.1186/s12967-022-03510-8.
6
Cancer-Associated Fibroblasts in Conversation with Tumor Cells in Endometrial Cancers: A Partner in Crime.癌症相关成纤维细胞与子宫内膜癌肿瘤细胞的对话:共犯关系。
Int J Mol Sci. 2021 Aug 24;22(17):9121. doi: 10.3390/ijms22179121.
7
Significance of Cancer-Associated Fibroblasts in the Interactions of Cancer Cells with the Tumor Microenvironment of Heterogeneous Tumor Tissue.癌症相关成纤维细胞在癌细胞与异质性肿瘤组织肿瘤微环境相互作用中的意义
Cancers (Basel). 2023 Apr 28;15(9):2536. doi: 10.3390/cancers15092536.
8
Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment.单细胞测序揭示了人类脑转移微环境的全景图。
Commun Biol. 2023 Jul 21;6(1):760. doi: 10.1038/s42003-023-05124-2.
9
MYL9 expressed in cancer-associated fibroblasts regulate the immune microenvironment of colorectal cancer and promotes tumor progression in an autocrine manner.MYL9 在癌症相关成纤维细胞中的表达通过自分泌方式调节结直肠癌的免疫微环境并促进肿瘤进展。
J Exp Clin Cancer Res. 2023 Nov 6;42(1):294. doi: 10.1186/s13046-023-02863-2.
10
Cancer-associated fibroblasts and the tumor microenvironment in non-small cell lung cancer.非小细胞肺癌中的癌症相关成纤维细胞与肿瘤微环境
Expert Rev Anticancer Ther. 2022 Feb;22(2):169-182. doi: 10.1080/14737140.2022.2019018. Epub 2022 Jan 2.

引用本文的文献

1
Involvement of Hormone Receptors, Membrane Receptors and Signaling Pathways in European Gastric Cancers Regarding Subtypes and Epigenetic Alterations: A Pilot Study.激素受体、膜受体及信号通路在欧洲胃癌中的作用与亚型及表观遗传改变的关系:一项初步研究
Biomedicines. 2025 Jul 24;13(8):1815. doi: 10.3390/biomedicines13081815.
2
Tissue inhibitor of metalloproteinase 1 as a biomarker of venous invasion in pancreatic ductal adenocarcinoma.金属蛋白酶组织抑制剂1作为胰腺导管腺癌静脉侵犯的生物标志物
Am J Cancer Res. 2025 Mar 15;15(3):1248-1263. doi: 10.62347/OVUJ4436. eCollection 2025.
3
Functionalized biomimetic nanoparticles loaded with salvianolic acid B for synergistic targeted triple-negative breast cancer treatment.负载丹酚酸B的功能化仿生纳米颗粒用于协同靶向治疗三阴性乳腺癌
Mater Today Bio. 2025 Jan 1;30:101441. doi: 10.1016/j.mtbio.2024.101441. eCollection 2025 Feb.
4
Biomaterials' enhancement of immunotherapy for breast cancer by targeting functional cells in the tumor micro-environment.生物材料通过靶向肿瘤微环境中的功能细胞增强乳腺癌的免疫疗法。
Front Immunol. 2024 Nov 12;15:1492323. doi: 10.3389/fimmu.2024.1492323. eCollection 2024.
5
Cancer‑associated fibroblasts under therapy‑induced senescence in the tumor microenvironment (Review).肿瘤微环境中处于治疗诱导衰老状态的癌症相关成纤维细胞(综述)
Exp Ther Med. 2024 Feb 20;27(4):150. doi: 10.3892/etm.2024.12438. eCollection 2024 Apr.

本文引用的文献

1
Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer.癌相关成纤维细胞再利用癌细胞衍生的乳酸来维持胰腺癌中的纤维性和免疫抑制性微环境。
JCI Insight. 2023 Oct 23;8(20):e163022. doi: 10.1172/jci.insight.163022.
2
Cancer-Associated Fibroblasts: The Origin, Biological Characteristics and Role in Cancer-A Glance on Colorectal Cancer.癌症相关成纤维细胞:起源、生物学特性及其在癌症中的作用——以结直肠癌为例
Cancers (Basel). 2022 Sep 9;14(18):4394. doi: 10.3390/cancers14184394.
3
Cancer-associated fibroblasts in breast cancer: Challenges and opportunities.乳腺癌中的癌相关成纤维细胞:挑战与机遇。
Cancer Commun (Lond). 2022 May;42(5):401-434. doi: 10.1002/cac2.12291. Epub 2022 Apr 28.
4
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4 and PDPN CAFs to clinical outcome.癌症相关成纤维细胞组成随乳腺癌进展而变化,将S100A4和PDPN癌症相关成纤维细胞的比例与临床结果联系起来。
Nat Cancer. 2020 Jul;1(7):692-708. doi: 10.1038/s43018-020-0082-y. Epub 2020 Jun 29.
5
Lactate in the tumour microenvironment: From immune modulation to therapy.肿瘤微环境中的乳酸:从免疫调节到治疗。
EBioMedicine. 2021 Nov;73:103627. doi: 10.1016/j.ebiom.2021.103627. Epub 2021 Oct 14.
6
The Cellular Origins of Cancer-Associated Fibroblasts and Their Opposing Contributions to Pancreatic Cancer Growth.癌症相关成纤维细胞的细胞起源及其对胰腺癌生长的相反作用
Front Cell Dev Biol. 2021 Sep 27;9:743907. doi: 10.3389/fcell.2021.743907. eCollection 2021.
7
The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis.癌症相关成纤维细胞在癌症侵袭和转移中的作用
Cancers (Basel). 2021 Sep 21;13(18):4720. doi: 10.3390/cancers13184720.
8
The Role of Cancer-Associated Fibroblasts in Tumor Progression.癌症相关成纤维细胞在肿瘤进展中的作用。
Cancers (Basel). 2021 Mar 19;13(6):1399. doi: 10.3390/cancers13061399.
9
Co-targeting of CXCR4 and hedgehog pathways disrupts tumor-stromal crosstalk and improves chemotherapeutic efficacy in pancreatic cancer.双重靶向 CXCR4 和 hedgehog 通路破坏胰腺癌中的肿瘤-基质相互作用并提高化疗疗效。
J Biol Chem. 2020 Jun 19;295(25):8413-8424. doi: 10.1074/jbc.RA119.011748. Epub 2020 May 1.
10
[Research Progress of Cancer-associated Fibroblasts in Lung Cancer].肺癌中癌相关成纤维细胞的研究进展
Zhongguo Fei Ai Za Zhi. 2020 Apr 20;23(4):267-273. doi: 10.3779/j.issn.1009-3419.2020.102.16.

癌症相关成纤维细胞:肿瘤发展中的主要同谋者

Cancer-Associated Fibroblasts: Major Co-Conspirators in Tumor Development.

作者信息

Singh Shubhangi, Singh Ajay P, Mitra Ranjana

机构信息

Department of International Studies (Global Health), College of Arts and Sciences, University of South Alabama, Mobile, AL 36688, USA.

Cancer Biology Program, Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604, USA.

出版信息

Cancers (Basel). 2024 Jan 2;16(1):211. doi: 10.3390/cancers16010211.

DOI:10.3390/cancers16010211
PMID:38201638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10778099/
Abstract

The tumor microenvironment (TME) is a critical determinant of tumor progression, metastasis, and therapeutic outcomes [...].

摘要

肿瘤微环境(TME)是肿瘤进展、转移和治疗结果的关键决定因素[……]。