Department of Emergency Medicine, Mount Sinai West and Mount Sinai Morningside Hospitals, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
J Neurotrauma. 2024 Jul;41(13-14):1494-1508. doi: 10.1089/neu.2023.0517. Epub 2024 Feb 5.
Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Disparities exist in the populations that acquire TBIs, however, with a greater burden and poorer outcomes associated with communities of color and lower socioeconomic status. To combat health inequities such as these, institutions have begun to target social determinants of health (SDoH), which are environmental factors that affect health outcomes and risks. The SDoH may play a role in sustaining a TBI and provide modifiable targets for action to reduce the risk of TBI, especially in high-risk communities. In this study, we describe the existing literature regarding SDoH and their association with sustaining a TBI. We performed a scoping review with a comprehensive search of the Ovid MEDLINE/Embase databases. To summarize the literature, this review adapts the World Health Organization's Commission on SDoH's conceptual framework. Fifty-nine full-text articles, including five focusing on lower and middle-income countries, met our study criteria. Results of the scoping review indicate that several structural determinants of health were associated with TBI risk. Lower educational attainment and income levels were associated with higher odds of TBI. In addition, multiple studies highlight that minority populations were identified as having higher odds of TBI than their White counterparts. Literature highlighting intermediate determinants of health examined in this review describes associations between sustaining a TBI and rurality, work environment, medical conditions, medication/substance use, and adversity. Recommended exploration into lesser-researched SDoH is discussed, and the expansion of this review to other aspects of the TBI continuum is warranted.
创伤性脑损伤(TBI)是全球范围内导致死亡和残疾的主要原因。然而,获得 TBI 的人群存在差异,有色人种和社会经济地位较低的社区负担更大,结果更差。为了应对这些健康不平等问题,各机构已开始针对健康的社会决定因素(SDoH),即影响健康结果和风险的环境因素。SDoH 可能在维持 TBI 中发挥作用,并为减少 TBI 风险提供可改变的目标,尤其是在高风险社区。在这项研究中,我们描述了关于 SDoH 及其与维持 TBI 之间关联的现有文献。我们对 Ovid MEDLINE/Embase 数据库进行了全面搜索,开展了范围综述。为了总结文献,本综述采用了世界卫生组织社会决定因素委员会的概念框架。符合研究标准的全文文章有 59 篇,其中 5 篇专注于中低收入国家。范围综述的结果表明,健康的几个结构性决定因素与 TBI 风险有关。教育程度和收入水平较低与 TBI 的可能性较高相关。此外,多项研究强调少数民族群体被认为比白人发生 TBI 的可能性更高。本综述中描述的维持 TBI 与农村环境、工作环境、医疗条件、药物/物质使用和逆境等中间决定因素之间的关联。探讨了对研究较少的 SDoH 进行进一步探索的建议,并且有理由将本综述扩展到 TBI 连续体的其他方面。