• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

在一名等待法洛四联症初次修复手术的72岁患者中使用丙吡胺治疗法洛四联症发作。

Treating Tet Spells With Disopyramide in a 72-Year-Old Awaiting Primary Repair of Tetralogy of Fallot.

作者信息

Kalapurakal George T, Monaco James M

机构信息

Department of Cardiology, Advanced Heart Failure, Advocate Christ Medical Center, Chicago, Illinois, USA.

出版信息

JACC Case Rep. 2023 Nov 3;28:102093. doi: 10.1016/j.jaccas.2023.102093. eCollection 2023 Dec 20.

DOI:10.1016/j.jaccas.2023.102093
PMID:38204534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10774763/
Abstract

An adult with unrepaired tetralogy of Fallot presented with frequent tet spells. Her course was complicated by severe cyanotic spells and tachycardia-bradycardia syndrome that limited beta blocker use to stabilize her spells. She markedly improved after disopyramide initiation and underwent successful tetralogy of Fallot repair with excellent functional outcome.

摘要

一名患有未经修复的法洛四联症的成年人频繁出现缺氧发作。她的病情因严重的青紫发作和心动过速-心动过缓综合征而复杂化，这限制了β受体阻滞剂的使用以稳定发作。在开始使用丙吡胺后，她的病情明显改善，并成功接受了法洛四联症修复手术，功能预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/c93fb3db890a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/79c53d8b76e1/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/e71c5a91ed66/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/c93fb3db890a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/79c53d8b76e1/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/e71c5a91ed66/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6925/10774763/c93fb3db890a/gr2.jpg

相似文献

1
Treating Tet Spells With Disopyramide in a 72-Year-Old Awaiting Primary Repair of Tetralogy of Fallot.在一名等待法洛四联症初次修复手术的72岁患者中使用丙吡胺治疗法洛四联症发作。
JACC Case Rep. 2023 Nov 3;28:102093. doi: 10.1016/j.jaccas.2023.102093. eCollection 2023 Dec 20.
2
Does the prophylactic and therapeutic use of beta-blockers in preoperative patients with tetralogy of Fallot significantly prevent and treat the occurrence of cyanotic spells?对于法洛四联症术前患者预防性及治疗性使用β受体阻滞剂能否显著预防和治疗青紫发作？
Interact Cardiovasc Thorac Surg. 2017 Oct 1;25(4):647-650. doi: 10.1093/icvts/ivx135.
3
Acute Esophageal Necrosis Secondary to Cyanotic Spells Associated with Unrepaired Tetralogy of Fallot.继发于未修补的法洛四联症相关紫绀发作的急性食管坏死。
Int Heart J. 2023 May 31;64(3):506-511. doi: 10.1536/ihj.22-700. Epub 2023 May 16.
4
Treatment of tetralogy of Fallot hypoxic spell with intranasal fentanyl.经鼻内用芬太尼治疗法洛四联症缺氧发作。
Pediatrics. 2014 Jul;134(1):e266-9. doi: 10.1542/peds.2013-3183. Epub 2014 Jun 16.
5
Propranolol Therapy in Tetralogy of Fallot: Treating the Echocardiogram or Treating the Patient.法洛四联症的普萘洛尔治疗：治疗超声心动图表现还是治疗患者本身。
Pediatr Cardiol. 2025 Aug;46(6):1643-1648. doi: 10.1007/s00246-024-03580-z. Epub 2024 Jul 17.
6
Mechanism of cyanotic spells in tetralogy of Fallot--the missing link?法洛四联症中青紫发作的机制——缺失的环节？
Int J Cardiol. 1992 Oct;37(1):1-5. doi: 10.1016/0167-5273(92)90125-m.
7
Pheochromocytoma and tetralogy of Fallot: a rare but potentially dangerous combination.
Endocr Pract. 2014 May;20(5):e80-5. doi: 10.4158/EP13408.CR.
8
A rare case of Tetralogy of Fallot with right atrial thrombus presenting with hemiplegia complicating the clinical course.罕见法洛四联症合并右心房血栓形成致偏瘫病例，使临床过程复杂化。
J Card Surg. 2021 Oct;36(10):3901-3904. doi: 10.1111/jocs.15792. Epub 2021 Jul 9.
9
A uniform strategy of primary repair of tetralogy of Fallot: Transventricular approach results in low reoperation rate in the first decade.法洛四联症一期修复的统一策略：经心室入路导致十年内再次手术率较低。
J Thorac Cardiovasc Surg. 2023 Dec;166(6):1731-1738.e3. doi: 10.1016/j.jtcvs.2023.05.036. Epub 2023 Jun 9.
10
Anaesthesia management for cleft lip in a child with unrepaired Tetralogy of Fallot in Malawi: a case report.马拉维一名法洛四联症未修复的患儿行唇裂麻醉管理：病例报告。
Malawi Med J. 2022 Sep;34(3):201-203. doi: 10.4314/mmj.v34i3.9.

本文引用的文献

1
Safety of Outpatient Initiation of Disopyramide for Obstructive Hypertrophic Cardiomyopathy Patients.门诊为梗阻性肥厚型心肌病患者起始使用丙吡胺的安全性。
J Am Heart Assoc. 2017 May 26;6(6):e005152. doi: 10.1161/JAHA.116.005152.
2
Unrepaired tetralogy of fallot in an 85-year-old man.一名85岁男性的未修复法洛四联症。
Congenit Heart Dis. 2012 Sep-Oct;7(5):E78-81. doi: 10.1111/j.1747-0803.2012.00642.x. Epub 2012 Apr 3.
3
Tetralogy of fallot: yesterday and today.法洛四联症：过去与现在。
World J Surg. 2010 Apr;34(4):658-68. doi: 10.1007/s00268-009-0296-8.
4
Disopyramide improves hypoxia in patients with tetralogy of Fallot through a negative inotropic action.
Jpn Circ J. 1999 Mar;63(3):160-4. doi: 10.1253/jcj.63.160.
5
Ventricular arrhythmia in unrepaired and repaired tetralogy of Fallot. Relation to age, timing of repair, and haemodynamic status.法洛四联症未修复和已修复情况下的室性心律失常。与年龄、修复时机及血流动力学状态的关系。
Br Heart J. 1984 Jul;52(1):77-81. doi: 10.1136/hrt.52.1.77.
6
Fallot's tetralogy--natural history.法洛四联症——自然病史
Singapore Med J. 1973 Sep;14(3):169-71.
7
Myocardial degeneration in congenital heart disease. Comparison of morphologic findings in young and old patients with congenital heart disease associated with muscular obstruction to right ventricular outflow.
Am J Cardiol. 1977 Jun;39(7):1051-63. doi: 10.1016/s0002-9149(77)80221-x.