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采用氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描（FDG-PET/CT）引导下的免疫抑制剂治疗孤立性冠状动脉炎以打破支架内再狭窄的恶性循环。

Isolated Coronary Arteritis Treated With FDG-PET/CT-Guided Immunosuppressant to Break the Vicious Cycle of In-Stent Restenosis.

作者信息

Takasaki Akihiro, Kurita Tairo, Hirota Yumi, Uno Kenta, Kirii Yosuke, Ichikawa Mizuki, Ishiyama Masaki, Terashima Mitsuyasu, Nakajima Ayako, Dohi Kaoru

机构信息

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.

Department of Cardiology, Toyohashi Heart Center, Toyohashi, Aichi, Japan.

出版信息

JACC Case Rep. 2023 Nov 15;28:102102. doi: 10.1016/j.jaccas.2023.102102. eCollection 2023 Dec 20.

DOI:10.1016/j.jaccas.2023.102102
PMID:38204559
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10774826/
Abstract

Recurrent in-stent restenosis of the coronary artery is a rare but intractable problem. In this situation, coronary arteritis should be considered as an etiology. This case highlights the use of immunosuppressive drugs, including tocilizumab, and follow-up F-18-fluorodeoxyglucose positron emission tomography/computed tomography to break the vicious circle of recurrent stenosis caused by isolated coronary arteritis of unknown cause.

摘要

冠状动脉支架内再狭窄是一个罕见但棘手的问题。在这种情况下，应考虑冠状动脉炎作为病因。本病例突出了使用包括托珠单抗在内的免疫抑制药物，以及后续的F-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描，以打破由不明原因的孤立性冠状动脉炎引起的再狭窄恶性循环。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/6311b907b6e8/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/9c3b694f7f03/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/075272e84169/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/9bbbcd451064/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/6311b907b6e8/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/9c3b694f7f03/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/075272e84169/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/9bbbcd451064/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e889/10774826/6311b907b6e8/gr3.jpg

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本文引用的文献

1
Intravascular ultrasound imaging of isolated and non aorto-ostial coronary Takayasu arteritis: a case report.孤立性非主动脉弓段冠状动脉 Takayasu 动脉炎的血管内超声成像：病例报告。
BMC Cardiovasc Disord. 2020 Jun 1;20(1):260. doi: 10.1186/s12872-020-01541-x.
2
Tocilizumab treatment effectively improves coronary artery involvement in patients with Takayasu arteritis.托珠单抗治疗有效改善 Takayasu 动脉炎患者的冠状动脉受累。
Clin Rheumatol. 2020 Aug;39(8):2369-2378. doi: 10.1007/s10067-020-05005-7. Epub 2020 Mar 6.
3
The Utility of FDG PET/CT in IgG4-Related Disease with a Focus on Coronary Artery Involvement.
18F-氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描（FDG PET/CT）在IgG4相关性疾病中的应用，重点关注冠状动脉受累情况
Nucl Med Mol Imaging. 2018 Feb;52(1):53-61. doi: 10.1007/s13139-017-0494-5. Epub 2017 Sep 18.
4
Efficacy of Biological-Targeted Treatments in Takayasu Arteritis: Multicenter, Retrospective Study of 49 Patients.生物靶向治疗在多发性大动脉炎中的疗效：49 例患者的多中心回顾性研究。
Circulation. 2015 Nov 3;132(18):1693-700. doi: 10.1161/CIRCULATIONAHA.114.014321. Epub 2015 Sep 9.
5
The role of 18F-FDG PET/CT in large-vessel vasculitis: appropriateness of current classification criteria?18F-FDG PET/CT在大血管血管炎中的作用：当前分类标准是否合适？
Biomed Res Int. 2014;2014:687608. doi: 10.1155/2014/687608. Epub 2014 Aug 14.
6
Mechanism of late in-stent restenosis after implantation of a paclitaxel derivate-eluting polymer stent system in humans.紫杉醇衍生物洗脱聚合物支架系统植入人体后晚期支架内再狭窄的机制
Circulation. 2002 Nov 19;106(21):2649-51. doi: 10.1161/01.cir.0000041632.02514.14.