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高钙血症危象：尤因肉瘤的一种罕见表现

Hypercalcemic Crisis: A Rare Presentation of Ewing's Sarcoma.

作者信息

Haldhar Abhijeet, Lohar Rajshekhar, Kumbhar Saurabh S, Kant Ravi, Dhar Minakshi

机构信息

Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

College of Nursing, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

出版信息

Cureus. 2023 Dec 11;15(12):e50339. doi: 10.7759/cureus.50339. eCollection 2023 Dec.

DOI:10.7759/cureus.50339
PMID:38205477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10781019/
Abstract

Ewing's sarcoma (ES) is a rare malignancy of adolescence that usually presents with clinically apparent disease involving long bones, brought to attention by trauma and/or fractures. Hypercalcemia of malignancy is a well-known phenomenon; however, hypercalcemia is exceptionally rare in ES. This case report discusses a 20-year-old lady who experienced chronic bone pains in her hip and lower limbs, ultimately leading to a hypercalcemic crisis. We emphasize the importance of considering ES as a potential cause of hypercalcemia, highlighting the mechanism, diagnostic and therapeutic challenges, the associated poor prognosis, and the necessity for a multidisciplinary approach to managing the condition.

摘要

尤因肉瘤（ES）是一种罕见的青少年恶性肿瘤，通常表现为累及长骨的临床明显疾病，因创伤和/或骨折而引起关注。恶性肿瘤高钙血症是一种众所周知的现象；然而，高钙血症在ES中极为罕见。本病例报告讨论了一名20岁女性，她经历了髋部和下肢的慢性骨痛，最终导致高钙血症危象。我们强调将ES视为高钙血症潜在病因的重要性，突出其机制、诊断和治疗挑战、相关的不良预后，以及采用多学科方法管理该疾病的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/9e36912957b0/cureus-0015-00000050339-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/f9699735c6a0/cureus-0015-00000050339-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/2e50f469beb4/cureus-0015-00000050339-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/b7a6a1c5070c/cureus-0015-00000050339-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/f2dc3f075b12/cureus-0015-00000050339-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/6faca7f820b5/cureus-0015-00000050339-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/56fd44366664/cureus-0015-00000050339-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/27f22debe7b5/cureus-0015-00000050339-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/9e36912957b0/cureus-0015-00000050339-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/f9699735c6a0/cureus-0015-00000050339-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/2e50f469beb4/cureus-0015-00000050339-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/b7a6a1c5070c/cureus-0015-00000050339-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/f2dc3f075b12/cureus-0015-00000050339-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/6faca7f820b5/cureus-0015-00000050339-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/56fd44366664/cureus-0015-00000050339-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/27f22debe7b5/cureus-0015-00000050339-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96de/10781019/9e36912957b0/cureus-0015-00000050339-i08.jpg

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