Hussein Tharwat W, Almualem Zahra D, Almualem Fatema D, Zainaldeen Bushra A, Alshaikh Zainab J
Hematology, Salmaniya Medical Complex, Manama, BHR.
Internal Medicine, Salmaniya Medical Complex, Manama, BHR.
Cureus. 2023 Dec 11;15(12):e50325. doi: 10.7759/cureus.50325. eCollection 2023 Dec.
A leukemoid reaction is a rare condition characterized by an elevation in white blood cell count exceeding 50,000 cells/μL in response to severe medical conditions, which can mimic the presentation of chronic myeloid leukemia (CML). Distinguishing between leukemoid reaction and CML depends on a thorough clinical history and comprehensive laboratory evaluation. We present a case of leukemoid reaction associated with severe diabetic ketoacidosis, where the patient's white blood cell count returned to the normal range after the correction of hyperglycemia and electrolyte imbalances.
类白血病反应是一种罕见病症,其特征为因严重疾病导致白细胞计数升高超过50,000个/μL,可模仿慢性粒细胞白血病(CML)的表现。区分类白血病反应和CML取决于详尽的临床病史和全面的实验室评估。我们报告一例与严重糖尿病酮症酸中毒相关的类白血病反应病例,该患者在高血糖和电解质失衡得到纠正后白细胞计数恢复到正常范围。