• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

幼儿严重糖尿病酮症酸中毒伴类白血病反应及昏迷:一例报告

Severe Diabetic Ketoacidosis With Leukemoid Reaction and Coma in a Toddler: A Case Report.

作者信息

Burlaka Ievgeniia, Babii Serhii, Kovalchuk Ihor

机构信息

Department of Pediatrics №4, Bogomolets National Medical University, Kyiv, Ukraine.

出版信息

Clin Med Insights Case Rep. 2025 Sep 16;18:11795476251375551. doi: 10.1177/11795476251375551. eCollection 2025.

DOI:10.1177/11795476251375551
PMID:40969238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12441270/
Abstract

We present a case of a 3-year-old girl with previously diagnosed type 1 diabetes mellitus (T1DM) who was admitted in an unconscious state with severe diabetic ketoacidosis (DKA), lactic acidosis, and coma. The condition was complicated by profound dehydration, leukemoid reaction of neutrophilic type, and reactive thrombocytosis. Early intensive care management, mechanical ventilation, and insulin therapy led to stabilization and gradual recovery. This case highlights the critical importance of early recognition, aggressive management, and multidisciplinary care in pediatric patients with complicated DKA.

摘要

我们报告一例3岁女童,此前已诊断为1型糖尿病(T1DM),因严重糖尿病酮症酸中毒(DKA)、乳酸酸中毒和昏迷而意识不清入院。病情并发严重脱水、嗜中性粒细胞型类白血病反应和反应性血小板增多症。早期强化护理管理、机械通气和胰岛素治疗使病情稳定并逐渐康复。该病例突出了对患有复杂DKA的儿科患者进行早期识别、积极治疗和多学科护理的至关重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/001a/12441270/e7aabb4c114b/10.1177_11795476251375551-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/001a/12441270/e7aabb4c114b/10.1177_11795476251375551-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/001a/12441270/e7aabb4c114b/10.1177_11795476251375551-fig1.jpg

相似文献

1
Severe Diabetic Ketoacidosis With Leukemoid Reaction and Coma in a Toddler: A Case Report.幼儿严重糖尿病酮症酸中毒伴类白血病反应及昏迷:一例报告
Clin Med Insights Case Rep. 2025 Sep 16;18:11795476251375551. doi: 10.1177/11795476251375551. eCollection 2025.
2
Pediatric Diabetic Ketoacidosis (PDKA) among newly diagnosed diabetic patients at Dilla University Hospital, Dilla, Ethiopia: Prevalence and predictors.埃塞俄比亚迪拉市迪拉大学医院新诊断糖尿病患者中的小儿糖尿病酮症酸中毒(PDKA):患病率及预测因素
PLoS One. 2025 Jan 30;20(1):e0314433. doi: 10.1371/journal.pone.0314433. eCollection 2025.
3
SGLT2 Inhibitors: A Systematic Review of Diabetic Ketoacidosis and Related Risk Factors in the Primary Literature.钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂:对原发性文献中糖尿病酮症酸中毒及相关危险因素的系统评价
Pharmacotherapy. 2017 Feb;37(2):187-194. doi: 10.1002/phar.1881. Epub 2017 Jan 16.
4
GA/HbA1c Ratio Predicts the Occurrence of Diabetic Ketoacidosis and Disease Severity in Children with Type 1 Diabetes Mellitus.GA/HbA1c比值可预测1型糖尿病儿童糖尿病酮症酸中毒的发生及疾病严重程度。
Clin Lab. 2025 Jul 1;71(7). doi: 10.7754/Clin.Lab.2024.241225.
5
Diabetic ketoacidosis in patients exposed to antipsychotics: a systematic literature review and analysis of Danish adverse drug event reports.暴露于抗精神病药物的患者中的糖尿病酮症酸中毒:一项系统文献综述及对丹麦药品不良事件报告的分析
Psychopharmacology (Berl). 2016 Oct;233(21-22):3663-3672. doi: 10.1007/s00213-016-4411-x. Epub 2016 Sep 4.
6
Combined diabetic ketoacidosis and hyperosmolar hyperglycemic state in type 1 diabetes mellitus induced by immune checkpoint inhibitors: Underrecognized and underreported emergency in ICIs-DM.免疫检查点抑制剂诱导的 1 型糖尿病合并糖尿病酮症酸中毒和高渗高血糖综合征:ICI-DM 中的未被充分认识和报告的紧急情况。
Front Endocrinol (Lausanne). 2023 Jan 4;13:1084441. doi: 10.3389/fendo.2022.1084441. eCollection 2022.
7
Subcutaneous rapid-acting insulin analogues for diabetic ketoacidosis.用于糖尿病酮症酸中毒的皮下速效胰岛素类似物。
Cochrane Database Syst Rev. 2016 Jan 21;2016(1):CD011281. doi: 10.1002/14651858.CD011281.pub2.
8
Recurrent diabetic ketoacidosis in Saudi patients with type 1 diabetes mellitus: a retrospective study from a tertiary hospital.沙特1型糖尿病患者复发性糖尿病酮症酸中毒:来自一家三级医院的回顾性研究。
Ann Saudi Med. 2025 Aug 28:1-8. doi: 10.5144/0256-4947.2025.28.08.1200.
9
Concurrence of clozapine-induced diabetic ketoacidosis and neuroleptic malignant syndrome: A case report.氯氮平诱发糖尿病酮症酸中毒与抗精神病药恶性综合征并存:一例报告
Medicine (Baltimore). 2025 Aug 22;104(34):e44172. doi: 10.1097/MD.0000000000044172.
10
Characterisation of diabetic ketoacidosis in children and adolescents with type 1 diabetes: a regional hospital study.1型糖尿病儿童及青少年糖尿病酮症酸中毒的特征:一项地区医院研究。
BMC Pediatr. 2025 Jun 7;25(1):463. doi: 10.1186/s12887-025-05824-0.