Ueda M, Fujimoto T, Becker A E
Jpn Heart J. 1986 Sep;27(5):635-43. doi: 10.1536/ihj.27.635.
The observation that subpulmonary or doubly committed subarterial ventricular septal defects occur with a high frequency among orientals as compared to westerners has led to the hypothesis that a racial difference exists with regard to normal and abnormal development of the embryonic conal septum. In an attempt to contribute to this concept we have studied 24 normal hearts and 70 hearts with a perimembranous ventricular septal defect from patients of Japanese and Dutch origin. The length of the infundibular septum and the length of the right ventricle were not statistically different between the 2 groups. These findings suggest that in normal hearts and in hearts with perimembranous ventricular septal defects no racial differences exist with respect to the role of the embryonic conal septum in contributing to the definitive infundibular septum. The results indicate that subpulmonary or doubly committed subarterial defects may have a different origin from that of the usual perimembranous defect.
与西方人相比，东方人肺下型或双动脉下型室间隔缺损的发生率较高，这一观察结果引发了一种假说，即胚胎圆锥间隔的正常和异常发育存在种族差异。为了对这一概念有所贡献，我们研究了来自日本和荷兰的24例正常心脏以及70例患有膜周部室间隔缺损的心脏。两组之间漏斗间隔的长度和右心室的长度在统计学上没有差异。这些发现表明，在正常心脏和患有膜周部室间隔缺损的心脏中，胚胎圆锥间隔在形成最终漏斗间隔中所起的作用不存在种族差异。结果表明，肺下型或双动脉下型缺损的起源可能与常见的膜周部缺损不同。
